IL-4-induced caveolin-1-containing lipid rafts aggregation contributes to MUC5AC synthesis in bronchial epithelial cells

被引：0
|
作者：
Yu Xia
Peng-Cheng Cai
Fan Yu
Liang Xiong
Xin-Liang He
Shan-Shan Rao
Feng Chen
Xiang-Ping Yang
Wan-Li Ma
Hong Ye
机构：
[1] Huazhong University of Science and Technology,Department of Pathophysiology, School of Basic Medicine, Tongji Medical College
[2] Huazhong University of Science and Technology,Department of Clinical Laboratory, Union Hospital, Tongji Medical College
[3] Huazhong University of Science and Technology,Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College
[4] Nanjing Medical University,Department of Forensic Medicine
[5] Huazhong University of Science and Technology,Department of Immunology, School of Basic Medicine, Tongji Medical College
[6] Key Laboratory of Pulmonary Diseases,undefined
[7] Ministry of Health of China,undefined
来源：
Respiratory Research | / 18卷
关键词：
IL-4; Bronchial epithelial cells; Lipid rafts; Intracellular Ca;  ; MUC5AC; Asthma;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] The protective effects of Omarigliptin against Lipopolysaccharide (LPS)-induced inflammatory response and expression of mucin 5AC (MUC5AC) in human bronchial epithelial cells
    Ma, Libin
    Chang, Enqiang
    Ruan, Xiaoguo
    Zhang, Beibei
    Tang, Fudong
    Zhang, Jiaqiang
    MOLECULAR IMMUNOLOGY, 2022, 141 : 108 - 115
  • [22] The Role of Nox4 in Oxidative Stress-Induced MUC5AC Overexpression in Human Airway Epithelial Cells
    Kim, Hyun Jik
    Park, Young-Duck
    Moon, Uk Yeol
    Kim, Jun-Hee
    Leon, Ju Hyun
    Lee, Jeung-Gweon
    Bae, Yun Soo
    Yoon, Joo-Heon
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2008, 39 (05) : 598 - 609
  • [23] Phosphodiesterase 4 inhibition decreases MUC5AC expression induced by epidermal growth factor in human airway epithelial cells
    Mata, M
    Sarriá, B
    Buenestado, A
    Cortijo, J
    Cerdá, M
    Morcillo, EJ
    THORAX, 2005, 60 (02) : 144 - 152
  • [24] Heme Oxygenase-1 Could Suppress Il-13 Induced Goblet Cell Hyperplasia And Muc5ac Production Through Clca1 In Normal Human Bronchial Epithelial Cells
    Mishina, K.
    Shinkai, M.
    Shimokawaji, T.
    Shinoda, M.
    Masuda, M.
    Tsukahara, T.
    Nagai, K.
    Watanabe, H.
    Kimura, Y.
    Nagashima, A.
    Hara, Y.
    Kodama, T.
    Takanaka, K.
    Toda, M.
    Tsukiji, J.
    Inoue, Y.
    Kudo, M.
    Rubin, B. K.
    Kaneko, T.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2015, 191
  • [25] Wood Smoke Particles Stimulate MUC5AC Overproduction by Human Bronchial Epithelial Cells Through TRPA1 and EGFR Signaling
    Memon, Tosifa A.
    Nguyen, Nam D.
    Burrell, Katherine L.
    Scott, Abigail F.
    Almestica-Roberts, Marysol
    Rapp, Emmanuel
    Deering-Rice, Cassandra E.
    Reilly, Christopher A.
    TOXICOLOGICAL SCIENCES, 2020, 174 (02) : 278 - 290
  • [26] Effect of Korean Red Ginseng and Rg3 on Asian Sand Dust-Induced MUC5AC, MUC5B, and MUC8 Expression in Bronchial Epithelial Cells
    Shin, Seung-Heon
    Ye, Mi-Kyung
    Lee, Dong-Won
    Kang, Byung-Jun
    Chae, Mi-Hyun
    MOLECULES, 2021, 26 (07):
  • [27] [6]-Gingerol suppresses interleukin-1β-induced MUC5AC gene expression in human airway epithelial cells
    Kim, Jeong Hong
    Chang, Jung Hyun
    Yoon, Joo-Heon
    Kwon, Soon Ho
    Bae, Jung Ho
    Kim, Kyung-Su
    AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 2009, 23 (04) : 385 - 391
  • [28] Effects of galectin-3 on MUC5AC and MUC5B expression and NF-κB pathway in bronchial epithelial cells induced by mycoplasma pneumoniae: A biopsychosocial approach
    Su, Huihui
    Feng, Qiuling
    Ji, Anyan
    Zhang, Fang
    Guo, Junying
    Ji, Jianping
    INTERNATIONAL JOURNAL OF MENTAL HEALTH NURSING, 2024, 33 : 52 - 52
  • [29] Relationship between calcium-activated chloride channel 1 and MUC5AC in goblet cell hyperplasia induced by interleukin-13 in human bronchial epithelial cells
    Yasuo, Masanori
    Fujimoto, Keisaku
    Tanabe, Tsuyoshi
    Yaegashi, Hironobu
    Tsushima, Kenji
    Takasuna, Keiichirou
    Koike, Takeshi
    Yamaya, Mutsuo
    Nikaido, Toshio
    RESPIRATION, 2006, 73 (03) : 347 - 359
  • [30] Il-13-Induced Muc5ac Expression And The Goblet Cell Hyperplasia Are Suppressed By Hemin-Induced Heme-Oxygenase 1 In Normal Human Bronchial Epithelial Cells Using Air-Liquid Interface
    Shinoda, M.
    Shinkai, M.
    Mishina, K.
    Nagai, K.
    Hashimoto, Y.
    Ota, S.
    Watanabe, K.
    Hara, Y.
    Tomaru, K.
    Yamaguchi, N.
    Negishi, K.
    Inoue, Y.
    Kudo, M.
    Sasaki, M.
    Ishigatsubo, Y.
    Kaneko, T.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 189
12345