Implications of Pharmacogenetic Testing for Patients Taking Warfarin or Clopidogrel

被引：0
|
作者：
Megan M. Donohue
David L. Tirschwell
机构：
[1] Harborview Medical Center,Department of Neurology
来源：
Current Neurology and Neuroscience Reports | 2011年 / 11卷
关键词：
Pharmacogenetics; Warfarin; Clopidogrel; Testing; Primary stroke prevention; Secondary stroke prevention; Polymorphism; Resistance; Variant; Anticoagulation; Platelet response; Drug response; Safety; Treatment algorithm;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Our knowledge of the pharmacogenetics of warfarin and clopidogrel continues to expand as we learn more about the individual genetic variations that contribute to the drugs’ efficacy and toxicity. We aim to review the recent developments in the field and discuss the clinical implications for the treatment of ischemic stroke patients. Despite recent advances, there is still insufficient data to suggest that routine genetic testing improves outcomes in patients treated with warfarin or clopidogrel for prevention of stroke.
引用
收藏
页码：52 / 60
页数：8
相关论文
共 50 条
  • [1] Implications of Pharmacogenetic Testing for Patients Taking Warfarin or Clopidogrel
    Donohue, Megan M.
    Tirschwell, David L.
    [J]. CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS, 2011, 11 (01) : 52 - 60
  • [2] Pharmacogenetics Testing: Implications for Cardiovascular Therapeutics with Clopidogrel and Warfarin
    George, Jacob
    Doney, Alex
    Palmer, Colin N.
    Lang, Chim C.
    [J]. CARDIOVASCULAR THERAPEUTICS, 2010, 28 (03) : 135 - 138
  • [3] ATTITUDES ON WARFARIN PHARMACOGENETIC TESTING IN CHINESE PATIENTS AND PUBLIC
    Chan, Sze Ling
    Low, Joshua Jun Wen
    Chia, Kee Seng
    Wee, Hwee-Lin
    [J]. INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE, 2014, 30 (01) : 113 - 120
  • [4] Pharmacogenetic Testing for Warfarin Sensitivity
    Lyon, Elaine
    McMillin, Gwen
    Melis, Roberta
    [J]. CLINICS IN LABORATORY MEDICINE, 2008, 28 (04) : 525 - 537
  • [5] Implications of Pharmacogenetic Testing for Clopidogrel Therapy in a Tertiary Healthcare Hospital in North India
    Amarapalli, Jayachandra
    Sharma, Prabhat
    Datta, Rajat
    Sharma, Anuka
    [J]. CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (07)
  • [6] Pediatric warfarin practice and pharmacogenetic testing
    Thornburg, Courtney D.
    Jones, Emma
    Bomgaars, Lisa
    Gage, Brian F.
    [J]. THROMBOSIS RESEARCH, 2010, 126 (02) : E144 - E146
  • [7] Pathology Consultation on Warfarin Pharmacogenetic Testing
    Stack, Gary
    [J]. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2011, 135 (01) : 13 - 19
  • [8] Positive predictive value of fecal occult blood testing in patients taking aspirin, other NSAIDS, warfarin or clopidogrel
    McDougall, Hcather E.
    Sawhney, Mandeep S.
    Nelson, Douglas B.
    Bond, John H.
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2007, 102 : S570 - S570
  • [9] The Long and Winding Road to Warfarin Pharmacogenetic Testing
    Ginsburg, Geoffrey S.
    Voora, Deepak
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2010, 55 (25) : 2813 - 2815
  • [10] Validation of Warfarin Pharmacogenetic Testing and Dosing Algorithm
    Fang, M.
    Roper, N.
    Walsh, S.
    Bona, R.
    [J]. JOURNAL OF MOLECULAR DIAGNOSTICS, 2008, 10 (06): : 567 - 567
12345