Pharmacogenetic Testing for Warfarin Sensitivity

被引：2
|
作者：
Lyon, Elaine [1 ,2 ]
McMillin, Gwen [1 ,2 ]
Melis, Roberta [2 ]
机构：
[1] Univ Utah, Dept Pathol, Salt Lake City, UT USA
[2] ARUP Inst Clin & Expt Pathol, Salt Lake City, UT USA
来源：
CLINICS IN LABORATORY MEDICINE | 2008年 / 28卷 / 04期
关键词：
D O I：
10.1016/j.cll.2008.09.001
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
With the US Food and Drug Administration's recent label change of warfarin to include genetic testing for warfarin sensitivity, manufacturers are developing assays, and laboratories are offering testing. This article describes the genetic variants for which testing is available. Current technologies and assays are compared, including considerations for laboratories in choosing a method. Finally, laboratory issues that apply to all methods, such as quality control and proficiency testing as well as service issues including turn-a round-time requirements are discussed.
引用
收藏
页码：525 / 537
页数：13
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