New isochaetochromin, an inhibitor of triacylglycerol synthesis in mammalian cells, produced by Penicillium sp. FKI-4942: II. structure elucidation

被引：0
|
作者：
Narihiro Ugaki
Hiroyuki Yamazaki
Ryuji Uchida
Hiroshi Tomoda
机构：
[1] Graduate School of Pharmaceutical Sciences,
[2] Kitasato University,undefined
来源：
The Journal of Antibiotics | 2012年 / 65卷
关键词：
fungal metabolites; isochaetochromin; naphtho-γ-pyrone; structure elucidation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The structure of a new congener of chaetochromin, an inhibitor of triacylglycerol synthesis in CHO-K1 cells produced by Penicillium sp. FKI-4942, was elucidated by spectroscopic methods, including various NMR experiments. Isochaetochromin A1 has a bis-naphtho-γ-pyrone moiety.
引用
收藏
页码：21 / 24
页数：3
相关论文
共 47 条
  • [21] Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1: II. Structure elucidation (vol 62, pg 207, 2009)
    Yamazaki, Hiroyuki
    Omura, Satoshi
    Tomoda, Hiroshi
    JOURNAL OF ANTIBIOTICS, 2009, 62 (11): : 653 - 654
  • [22] Pyloricidins, novel anti-Helicobacter pylori antibiotics produced by Bacillus sp.: II.: Isolation and structure elucidation
    Nagano, Y
    Ikedo, K
    Fujishima, A
    Izawa, M
    Tsubotani, S
    Nishimura, O
    Fujino, M
    JOURNAL OF ANTIBIOTICS, 2001, 54 (11): : 934 - 947
  • [23] Takanawaenes, novel antifungal antibiotics produced by Streptomyces sp. K99-5278 -: II.: Structure elucidation
    Fukuda, T
    Kim, YP
    Iizima, K
    Tomoda, H
    Omura, S
    JOURNAL OF ANTIBIOTICS, 2003, 56 (05): : 454 - 458
  • [24] Citridones, new potentiators of antifungal miconazole activity, produced by Penicillium sp FKH938-II.: Structure elucidation
    Fukuda, T
    Tomoda, H
    Omura, S
    JOURNAL OF ANTIBIOTICS, 2005, 58 (05): : 315 - 321
  • [25] Ferroverdins, inhibitors of cholesteryl ester transfer protein produced by Streptomyces sp. WK-5344 -: II.: Structure elucidation
    Tabata, N
    Tomoda, H
    Ömura, S
    JOURNAL OF ANTIBIOTICS, 1999, 52 (12): : 1108 - 1113
  • [26] Tripropeptins, novel antimicrobial agents produced by Lysobacter sp. II. structure elucidation (vol 57, pg 52, 2004)
    Hashizume, Hideki
    Hirosawa, Sehei
    Sawa, Ryuichi
    Muraoka, Yasuhiko
    Ikeda, Daishiro
    Naganawa, Hiroshi
    Igarashi, Masayuki
    JOURNAL OF ANTIBIOTICS, 2016, 69 (12): : 889 - 891
  • [27] Argifin, a new chitinase inhibitor, produced by Gliocladium sp FTD-0668 -: II.: Isolation, physico-chemical properties, and structure elucidation
    Arai, N
    Shiomi, K
    Iwai, Y
    Omura, S
    JOURNAL OF ANTIBIOTICS, 2000, 53 (06): : 609 - 614
  • [28] Deacetylravidomycin M, a new inhibitor of IL-4 signal transduction, produced by Streptomyces sp WK-6326 -: II.: Structure elucidation
    Arai, M
    Tomoda, H
    Tabata, N
    Ishiguro, N
    Kobayashi, S
    Omura, S
    JOURNAL OF ANTIBIOTICS, 2001, 54 (07): : 562 - 566
  • [29] Mathemycin A, a new antifungal macrolactone from actinomycete sp. HIL Y-8620959 - II. Structure elucidation
    Mukhopadhyay, T
    Vijayakumar, EKS
    Nadkarni, SR
    Fehlhaber, HW
    Kogler, H
    Petry, S
    JOURNAL OF ANTIBIOTICS, 1998, 51 (06): : 582 - 585
  • [30] New types of liposidomycins that inhibit bacterial peptidoglycan synthesis and are produced by Streptomyces -: II.: Isolation and structure elucidation
    Kimura, K
    Ikeda, Y
    Kagami, S
    Yoshihama, M
    Ubukata, M
    Esumi, Y
    Osada, H
    Isono, K
    JOURNAL OF ANTIBIOTICS, 1998, 51 (07): : 647 - 654
12345