Comparable Pharmacokinetics, Safety, and Tolerability of Etrolizumab Administered by Prefilled Syringe or Autoinjector in a Randomized Trial in Healthy Volunteers

被引：0
|
作者：
Wenhui Zhang
Helen Tyrrell
Han Ting Ding
Jennifer Pulley
Audrey Boruvka
Rich Erickson
Mariam Abouhossein
Renato Ravanello
Meina Tao Tang
机构：
[1] Genentech,
[2] Inc.,undefined
[3] Roche Products Limited,undefined
[4] Hoffmann-La Roche Limited,undefined
来源：
Advances in Therapy | 2021年 / 38卷
关键词：
Auto-injector; Crohn’s disease; Etrolizumab; Inflammatory bowel disease; Pharmacokinetic comparability; Prefilled syringe; Ulcerative colitis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：2418 / 2434
页数：16
相关论文
共 50 条
  • [41] Randomized Phase I Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Topical Daprodustat in Healthy Volunteers and in Patients With Diabetic Foot Ulcers
    Olson, Eric
    Mahar, Kelly M.
    Morgan, Lisa
    Fillmore, Christina
    Holland, Claire
    Lavery, Lawrence
    CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2019, 8 (06): : 765 - 778
  • [42] Pharmacokinetics and Gastrointestinal Tolerability of DMMET 01 (Glycinate of Metformin): Results of a Prospective Randomized Trial in Healthy Volunteers
    Garza-Ocanas, Lourdes
    Tamez-De La O, Eduardo
    Iglesias Chiesa, Jimena
    Gonzalez-Canudas, Jorge
    Rivas-Ruiz, Rodolfo
    DIABETES, 2009, 58 : A533 - A533
  • [43] Pharmacokinetics and tolerability of prefilled syringe and auto-injector presentations of MSB11456: results of a randomized, single-dose study in healthy adults
    Tomaszewska-Kiecana, Monika
    Dryja, Anna
    Ullmann, Martin
    Petit-Frere, Corinne
    Illes, Andras
    Dagres, Christos
    Monnet, Joelle
    EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 2023, 19 (04) : 447 - 455
  • [44] Comparison of pharmacokinetics, safety and tolerability of secukinumab administered subcutaneously using different delivery systems in healthy volunteers and in psoriasis patients
    Bruin, Gerard
    Hockey, Hans-Ulrich P.
    La Stella, Phillip
    Sigurgeirsson, Bardur
    Fu, Rong
    Patekar, Manmath
    Charef, Pascal
    Woessner, Ralph
    Boutouyrie-Dumont, Bruno
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 86 (02) : 338 - 351
  • [45] Pharmacokinetics, safety and tolerability of sub-lingually administered APL-130277 compared to subcutaneous apomorphine in healthy volunteers
    Agro, A.
    Dubow, J.
    Toong-Chow, L.
    Giovinazzo, A.
    MOVEMENT DISORDERS, 2015, 30 : S64 - S65
  • [46] Safety, tolerability, pharmacodynamics and pharmacokinetics of teverelix following single or repeated doses administered subcutaneously to healthy female volunteers.
    Maclean, CM
    Larsen, F
    Beglinger, C
    Piechatzek, R
    Drewe, J
    FERTILITY AND STERILITY, 2005, 84 : S352 - S353
  • [47] Pharmacokinetics, safety and tolerability of high-dose sub-lingually administered APL-130277 in healthy volunteers
    Agro, A.
    Dubow, J.
    Toong-Chow, L.
    Giovinazzo, A.
    MOVEMENT DISORDERS, 2015, 30 : S65 - S66
  • [48] A Randomized Phase 1 Dose Escalation Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Trabodenoson in Healthy Adult Volunteers
    Laties, Alan
    Rich, Cadmus C.
    Stoltz, Randall
    Humbert, Vernon
    Brickman, Chaim
    McVicar, William
    Baumgartner, Rudolf A.
    JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2016, 32 (08) : 548 - 554
  • [49] Comparison of pharmacokinetics and safety of pegfilgrastim administered by two delivery methods: on-body injector and manual injection with a prefilled syringe
    Bing-Bing Yang
    Phuong Khanh Morrow
    Xikun Wu
    Michael Moxness
    Desmond Padhi
    Cancer Chemotherapy and Pharmacology, 2015, 75 : 1199 - 1206
  • [50] Comparison of pharmacokinetics and safety of pegfilgrastim administered by two delivery methods: on-body injector and manual injection with a prefilled syringe
    Yang, Bing-Bing
    Phuong Khanh Morrow
    Wu, Xikun
    Moxness, Michael
    Padhi, Desmond
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2015, 75 (06) : 1199 - 1206
12345