Highlight report: towards the replacement of in vivo repeated dose systemic toxicity testing

被引:0
|
作者
Jan G. Hengstler
Rosemarie Marchan
Marcel Leist
机构
[1] Leibniz Research Centre for Working Environment and Human Factors (IfADo),Leibniz Institut für Arbeitsforschung an der TU Dortmund
[2] Universität Konstanz,Fachbereich Biologie
来源
Archives of Toxicology | 2012年 / 86卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:13 / 15
页数:2
相关论文
共 50 条
  • [21] New Approach Methodologies for assessing repeated-dose systemic toxicity: an outlook on progress made, gaps and challenges
    Ouedraogo, G.
    Detroyer, A.
    Riu, A.
    Gregoire, S.
    Gautier, F.
    Noel-Voisin, A.
    Bury, D.
    TOXICOLOGY LETTERS, 2023, 384 : S258 - S259
  • [22] Systemic Cobalt Toxicity Secondary to Metal-on-Metal Prosthetic Hip Replacement: a Case Report
    Blackmon, Jonathan
    Blackmon, Lindsey
    Goode, Claire
    Douthit, Nathan
    JOURNAL OF GENERAL INTERNAL MEDICINE, 2024, 39 (01) : 133 - 137
  • [23] Systemic Cobalt Toxicity Secondary to Metal-on-Metal Prosthetic Hip Replacement: a Case Report
    Jonathan Blackmon
    Lindsey Blackmon
    Claire Goode
    Nathan Douthit
    Journal of General Internal Medicine, 2024, 39 : 133 - 137
  • [25] Evaluation of a human iPSC-derived BBB model for repeated dose toxicity testing with cyclosporine A as model compound
    Wellens, Sara
    Dehouck, Lucie
    Chandrasekaran, Vidya
    Singh, Pranika
    Loiola, Rodrigo Azevedo
    Sevin, Emmanuel
    Exner, Thomas
    Jennings, Paul
    Gosselet, Fabien
    Culot, Maxime
    TOXICOLOGY IN VITRO, 2021, 73
  • [26] Repeated dose intramuscular injection of the CIMAvax-EGF vaccine in Sprague Dawley rats induces local and systemic toxicity
    Mancebo, A.
    Casaco, A.
    Gonzalez, B.
    Ledon, N.
    Sorlozabal, J.
    Leon, A.
    Gomez, D.
    Gonzalez, Y.
    Bada, A. M.
    Gonzalez, C.
    Arteaga, M. E.
    Ramirez, H.
    Fuentes, D.
    VACCINE, 2012, 30 (22) : 3329 - 3338
  • [27] Systemic and immunotoxicity of pristine and PEGylated multi-walled carbon nanotubes in an intravenous 28 days repeated dose toxicity study
    Zhang, Ting
    Tang, Meng
    Zhang, Shanshan
    Hu, Yuanyuan
    Li, Han
    Zhang, Tao
    Xue, Yuying
    Pu, Yuepu
    INTERNATIONAL JOURNAL OF NANOMEDICINE, 2017, 12 : 1539 - 1554
  • [28] Assessment of diurnal systemic dose of agrochemicals in regulatory toxicity testing - An integrated approach without additional animal use
    Saghir, Shakil A.
    Bartels, Michael J.
    Rick, David L.
    McCoy, Alene T.
    Rasoulpour, Reza J.
    Ellis-Hutchings, Robert G.
    Marty, M. Sue
    Terry, Claire
    Bailey, Jason P.
    Billington, Richard
    Bus, James S.
    REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2012, 63 (02) : 321 - 332
  • [29] Early-stage corneal toxicity secondary to high-dose systemic cytarabine: a case report
    Tsuyoshi Mito
    Shun Takeda
    Hisanori Miyashita
    Hiroshi Sasaki
    BMC Ophthalmology, 23
  • [30] Early-stage corneal toxicity secondary to high-dose systemic cytarabine: a case report
    Mito, Tsuyoshi
    Takeda, Shun
    Miyashita, Hisanori
    Sasaki, Hiroshi
    BMC OPHTHALMOLOGY, 2023, 23 (01)