Translational development of ABCB5+ dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers

被引：0

作者：

Andreas Kerstan

Kathrin Dieter

Elke Niebergall-Roth

Sabrina Klingele

Michael Jünger

Christoph Hasslacher

Georg Daeschlein

Lutz Stemler

Ulrich Meyer-Pannwitt

Kristin Schubert

Gerhard Klausmann

Titus Raab

Matthias Goebeler

Korinna Kraft

Jasmina Esterlechner

Hannes M. Schröder

Samar Sadeghi

Seda Ballikaya

Martin Gasser

Ana M. Waaga-Gasser

George F. Murphy

Dennis P. Orgill

Natasha Y. Frank

Christoph Ganss

Karin Scharffetter-Kochanek

Markus H. Frank

Mark A. Kluth

机构：

[1] University Hospital Würzburg,Department of Dermatology, Venereology and Allergology

[2] RHEACELL GmbH & Co. KG,Department of Dermatology

[3] TICEBA GmbH,Department of Clinical Research and Development

[4] University Hospital Greifswald,Department of Surgery

[5] Clinical Study Center St. Josefskrankenhaus,Division of Renal (Kidney) Medicine, Brigham and Women’s Hospital

[6] Diabetologikum DDG Ludwigshafen,Department of Dermatology, Brigham and Women’s Hospital

[7] MARE Clinic,Division of Plastic Surgery, Brigham and Women’s Hospital

[8] medamed GmbH,Department of Medicine

[9] Studienzentrum Aschaffenburg,Division of Genetics, Brigham and Women’s Hospital

[10] Diabetologikum Raab,Transplant Research Program

[11] University Hospital Würzburg,Harvard Stem Cell Institute

[12] Harvard Medical School,Department of Dermatology and Allergic Diseases

[13] Harvard Medical School,School of Medical and Health Sciences

[14] Harvard Medical School,Clinic of Dermatology, Immunology and Allergology

[15] VA Boston Healthcare System,undefined

[16] Harvard Medical School,undefined

[17] Boston Children’s Hospital,undefined

[18] Harvard Medical School,undefined

[19] Harvard University,undefined

[20] University Hospital,undefined

[21] Edith Cowan University,undefined

[22] Medical University Brandenburg “Theodor Fontane” Medical Center Dessau,undefined

来源：

Stem Cell Research & Therapy | / 13卷

关键词：

ABCB5; Advanced-therapy medicinal product; Angiogenesis; Chronic wound; Diabetic foot ulcer; Mesenchymal stem cells; Wound healing;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 25 条

[21] IL-1 signalling is up-regulated in chronic venous leg ulcers and represents a therapeutic target that is counteracted by dermal ABCB5+mesenchymal stem cells via secretion of interleukin-1 receptor antagonist
Vander Beken, S.
Meyer, P.
Sindrilaru, A.
Jiang, D.
de Vries, J. C.
Schatz, S.
Heinzl, A.
Kluth, A.
Over, B.
Miller, S.
Kettern, N.
Ganss, C.
Frank, N. Y.
Frank, M. H.
Wlaschek, M.
Scharffetter-Kochanek, K.
EXPERIMENTAL DERMATOLOGY, 2015, 24 (03) : E10 - E10
[22] Improved therapeutic effects on diabetic foot by human mesenchymal stem cells expressing MALAT1 as a sponge for microRNA-205-5p
Zhu, Lingyan
Zhong, Qiaoqing
Yang, Tianlun
Xiao, Xiangwei
AGING-US, 2019, 11 (24): : 12236 - 12245
[23] Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Facilitate Diabetic Wound Healing Through MiR-17-5p-mediated Enhancement of Angiogenesis
Qian Wei
Yaxi Wang
Kui Ma
Qiankun Li
Bingmin Li
Wenzhi Hu
Xiaobing Fu
Cuiping Zhang
Stem Cell Reviews and Reports, 2022, 18 : 1025 - 1040
[24] Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Facilitate Diabetic Wound Healing Through MiR-17-5p-mediated Enhancement of Angiogenesis
Wei, Qian
Wang, Yaxi
Ma, Kui
Li, Qiankun
Li, Bingmin
Hu, Wenzhi
Fu, Xiaobing
Zhang, Cuiping
STEM CELL REVIEWS AND REPORTS, 2022, 18 (03) : 1025 - 1040
[25] Improved wound healing of diabetic foot ulcers using human placenta-derived mesenchymal stem cells in gelatin electrospun nanofibrous scaffolds plus a platelet-rich plasma gel: A randomized clinical trial
Meamar, Rokhsareh
Ghasemi-Mobarakeh, Laleh
Norouzi, Mohammad-Reza
Siavash, Mansour
Hamblin, Michael R.
Fesharaki, Mehrafarin
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 101

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