Impact of cardiac rehabilitation exercise program on left ventricular diastolic function in coronary artery disease: a pilot study

被引:0
|
作者
Punsak Wuthiwaropas
Diego Bellavia
Mohamed Omer
Ray W. Squires
Christopher G. Scott
Patricia A. Pellikka
机构
[1] Mayo Clinic,Division of Cardiovascular Diseases, Department of Medicine
[2] Mayo Clinic,Division of Biomedical Statistics and Informatics, Department of Medicine
关键词
Coronary artery disease; Diastolic function; Echocardiography; Exercise;
D O I
暂无
中图分类号
学科分类号
摘要
Diastolic dysfunction is common in coronary artery disease (CAD). Exercise-based cardiac rehabilitation (CR) improves survival and quality of life but its effect on diastolic function is unclear. We sought to determine the impact of CR on diastolic function. We conducted a prospective study of CAD patients referred for 3-month outpatient CR, with pre-CR and post-CR echocardiograms. Twenty-five outpatients (age [mean ± SD], 66 ± 11 years; 7 [28 %] women; 22 [88 %] with recent acute coronary syndrome) were recruited upon beginning CR; one patient lacking follow-up was excluded from analysis. Before CR, patients’ mean ejection fraction was 61 ± 7 %; regional wall motion score index was 1.18 ± 0.28; and left ventricular diastolic dysfunction existed in 21 (88 %). Of the 24 (96 %) patients with post-CR follow-up, 12 (50 %) had improved diastolic function, 2 of the 24 (8 %) had normal diastolic function throughout, nine (38 %) remained at the same grade, and one (4 %) had worsened diastolic function. The E/e′ ratio improved significantly after CR (11.9 ± 4.5 vs. 10.7 ± 4.5; P = .048). Fourteen patients with normal or improved diastolic function had a greater decrease in left atrial volume index (−4.2 ± 6.3 vs. 1.6 ± 6.3 mL/m2; P = .04) and a greater increase in peak untwisting rate (20 ± 36 vs. −42 ± 45 °/s; P = .003) than did patients with no diastolic improvement. Three-month, exercise-based CR was associated with improved left ventricular diastolic function in half of our patients. Further large studies are needed to clarify the effect of CR on diastolic dysfunction in patients with CAD.
引用
收藏
页码:777 / 785
页数:8
相关论文
共 50 条
  • [41] Impact of coronary artery disease on left ventricular systolic function and geometry in hypertensive patients with left ventricular hypertrophy (the LIFE study)
    Zabalgoitia, M
    Berning, J
    Koren, MJ
    Stoylen, A
    Nieminen, MS
    Dahlöf, B
    Devereux, RB
    AMERICAN JOURNAL OF CARDIOLOGY, 2001, 88 (06): : 646 - 650
  • [42] EFFECT OF EXERCISE ON VENTRICULAR DIASTOLIC TIME IN CORONARY-ARTERY DISEASE
    SUGIURA, T
    IWASAKA, T
    TAKAHASHI, N
    MATSUTANI, M
    TAKAYAMA, Y
    INADA, M
    SPODICK, DH
    AMERICAN JOURNAL OF CARDIOLOGY, 1987, 59 (12): : 1089 - 1092
  • [43] Aggravation of left ventricular diastolic dysfunction in hypertensives with coronary artery disease
    Vlasseros, Ioannis
    Katsi, Vasiliki
    Vyssoulis, Gregory
    Pylarinos, Ioannis
    Richter, Dimitrios
    Gialernios, Theodoros
    Souretis, Georgios
    Tousoulis, Dimitris
    Stefanadis, Christodoulos
    Kallikazaros, Ioannis
    HYPERTENSION RESEARCH, 2013, 36 (10) : 885 - 888
  • [44] Cold exposure and left ventricular diastolic performance in coronary artery disease
    Kudaiberdieva, G
    Timuralp, B
    Ata, N
    Unalir, A
    Gorenek, B
    Cavusoglu, Y
    Goktekin, O
    Birdane, A
    ANGIOLOGY, 2003, 54 (02) : 187 - 193
  • [45] LEFT-VENTRICULAR DIASTOLIC FILLING IN CORONARY-ARTERY DISEASE
    MASUYAMA, T
    AMERICAN HEART JOURNAL, 1989, 118 (06) : 1357 - 1358
  • [46] Aggravation of left ventricular diastolic dysfunction in hypertensives with coronary artery disease
    Ioannis Vlasseros
    Vasiliki Katsi
    Gregory Vyssoulis
    Ioannis Pylarinos
    Dimitrios Richter
    Theodoros Gialernios
    Georgios Souretis
    Dimitris Tousoulis
    Christodoulos Stefanadis
    Ioannis Kallikazaros
    Hypertension Research, 2013, 36 : 885 - 888
  • [47] LEFT AND RIGHT VENTRICULAR SYSTOLIC FUNCTION AND EXERCISE CAPACITY WITH CORONARY-ARTERY DISEASE
    MORRISON, DA
    STOVALL, JR
    BARBIERE, C
    AMERICAN JOURNAL OF CARDIOLOGY, 1991, 67 (13): : 1079 - 1083
  • [48] The Effect of Cardiac Rehabilitation on Left Ventricular Remodeling in Men and Women Patients with Coronary Artery Disease
    Shabani, R.
    Nikoo, M.
    Gholamrezaei, Sh.
    Shirmohammadi, T.
    ARCHIVES OF REHABILITATION, 2013, 13 (04): : 132 - 139
  • [49] Prognostic Value of Left Ventricular Diastolic Dysfunction in Patients Undergoing Cardiac Catheterization for Coronary Artery Disease
    Fukuta, Hidekatsu
    Ohte, Nobuyuki
    Wakami, Kazuaki
    Goto, Toshihiko
    Tani, Tomomitsu
    Kimura, Genjiro
    CARDIOLOGY RESEARCH AND PRACTICE, 2012, 2012
  • [50] Extent and severity of coronary artery disease by coronary CT angiography is associated with elevated left ventricular diastolic pressures and worsening diastolic function
    Lin, Fay Y.
    Zemedkun, Micheas
    Dunning, Allison
    Gomez, Millie
    Labounty, Troy M.
    Asim, Muhammad
    Horn, Evelyn
    Aurigemma, Gerard
    Maurer, Matthew S.
    Roman, Mary
    Devereux, Richard
    Min, James K.
    JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY, 2013, 7 (05) : 289 - 296