Aspirin plus clopidogrel may reduce the risk of early neurologic deterioration in ischemic stroke patients carrying CYP2C19*2 reduced-function alleles

被引:0
|
作者
Xingyang Yi
Qiang Zhou
Chun Wang
Jing Lin
Zhenxiao Chai
机构
[1] People’s Hospital of Deyang City,Department of Neurology
[2] The Third Affiliated Hospital of Wenzhou Medical University,Department of Neurology
来源
Journal of Neurology | 2018年 / 265卷
关键词
Early neurological deterioration; Ischemic stroke; Clopidogrel; polymorphism; Dual antiplatelet therapy;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:2396 / 2403
页数:7
相关论文
共 50 条
  • [31] CYP2C19 LOF alleles confer no risk for HTPR but higher risk for recurrent ischemic events in clopidogrel treated elderly ACS patients
    Yang, Jie
    Wang, Xuyun
    Peng, Li
    Zhang, Lanning
    Li, Xiaoqi
    Liu, Jia
    Zhang, Yuxiao
    Xu, Qiang
    Lu, Caiyi
    Chen, Yundai
    Yin, Tong
    INTERNATIONAL JOURNAL OF CARDIOLOGY, 2015, 189 : 225 - 227
  • [32] Acute stent thrombosis after stent-assisted coiling in an intracranial aneurysm patient carrying two reduced-function CYP2C19 alleles A case report
    Ding, Lanping
    Gu, Zhichun
    Wang, Rong
    Li, Yichen
    Fang, Yun
    MEDICINE, 2017, 96 (47)
  • [33] A synergic effect between CYP2C19∗2, CYP2C19∗3 loss-of-function and CYP2C19∗17 gain-of-function alleles is associated with Clopidogrel resistance among Moroccan Acute Coronary Syndromes patients
    Hassani Idrissi H.
    Hmimech W.
    Khorb N.E.
    Akoudad H.
    Habbal R.
    Nadifi S.
    BMC Research Notes, 11 (1)
  • [34] CYP2C19 polymorphism and antiplatelet effects of clopidogrel in Chinese stroke patients
    Yang Jie
    Zhao Hong-Dong
    Tan Jie
    Ding Yun-Long
    Zou Jian-Jun
    PHARMAZIE, 2013, 68 (03): : 183 - 186
  • [35] Association with CYP2C19 polymorphisms and Clopidogrel in treatment of elderly stroke patients
    Changqing Li
    Weihua Jia
    Jian Li
    Fangfei Li
    Jing Ma
    Lichun Zhou
    BMC Neurology, 21
  • [36] Impact of CYP2C19 genotype in ischaemic stroke patients treated with clopidogrel
    Doney, A.
    Palmer, C.
    Morant, S.
    Flynn, R.
    MacDonald, T.
    INTERNATIONAL JOURNAL OF STROKE, 2015, 10 : 29 - 29
  • [37] Association with CYP2C19 polymorphisms and Clopidogrel in treatment of elderly stroke patients
    Li, Changqing
    Jia, Weihua
    Li, Jian
    Li, Fangfei
    Ma, Jing
    Zhou, Lichun
    BMC NEUROLOGY, 2021, 21 (01)
  • [38] Pharmacogenetics of CYP2C19 genetic polymorphism on clopidogrel response in patients with ischemic stroke from Saudi Arabia
    Alhazzani, Adel A.
    Munisamy, Murali
    Karunakaran, Gauthaman
    NEUROSCIENCES, 2017, 22 (01) : 31 - 37
  • [39] Association of CYP2C19 Polymorphisms With Clopidogrel Reactivity and Clinical Outcomes in Chronic Ischemic Stroke
    Tanaka, Tomotaka
    Yamagami, Hiroshi
    Ihara, Masafumi
    Miyata, Toshiyuki
    Miyata, Shigeki
    Hamasaki, Toshimitsu
    Amano, Shu
    Fukuma, Kazuki
    Yamamoto, Haruko
    Nakagawara, Jyoji
    Furui, Eisuke
    Uchiyama, Shinichiro
    Hyun, Boohan
    Yamamoto, Yasumasa
    Manabe, Yasuhiro
    Ito, Yasuhiro
    Fukunaga, Ryuzo
    Abumiya, Takeo
    Yasaka, Masahiro
    Kitagawa, Kazuo
    Toyoda, Kazunori
    Nagatsuka, Kazuyuki
    CIRCULATION JOURNAL, 2019, 83 (06) : 1385 - +
  • [40] Influence of CYP2C19 polymorphisms on platelet reactivity and clinical outcomes in ischemic stroke patients treated with clopidogrel
    Qiu, Li-Na
    Sun, Yan
    Wang, Lin
    Han, Rui-Fa
    Xia, Xiao-Shuang
    Liu, Jie
    Li, Xin
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2015, 747 : 29 - 35