Design and synthesis of novel antidiabetic agents

被引：0
|
作者：
Joon Yeol Lee
Won-Hui Park
Min-Kyoung Cho
Hyun Jin Yun
Byung-Ho Chung
Youngmi Kim Pak
Hoh-Gyu Hahn
Seung Hoon Cheon
机构：
[1] University of Ulsan,AsanInstitute for Life Sciences, Department of Internal Medicine, College of Medicine
[2] Korea Institute of Science and Technology,Life Science Division
[3] Chonnam National University,College of Pharmacy & Research Institute of Drug Development
来源：
Archives of Pharmacal Research | 2005年 / 28卷
关键词：
Antidiabetic agents; Quercetin; Thiazolidinedione; Malonate;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The synthesis and structure-activity relationships of a novel series of substituted quercetins that activates peroxisome proliferator-activated receptor gamma (PPARγ) are reported. The PPARγ agonistic activity of the most potent compound in this series is comparable to that of the thiazolidinedione-based antidiabetic drugs currently in clinical use.
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收藏
页码：142 / 150
页数：8
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