Synergy between sublethal doses of shikonin and metformin fully inhibits breast cancer cell migration and reverses epithelial-mesenchymal transition

被引:0
|
作者
Abolfazl Rostamian Tabari
Pegah Gavidel
Farzaneh Sabouni
Mossa Gardaneh
机构
[1] National Institute of Genetic Engineering and Biotechnology,
来源
Molecular Biology Reports | 2022年 / 49卷
关键词
Shikonin; Metformin; Breast cancer; MCF-7; Migration; Apoptosis;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:4307 / 4319
页数:12
相关论文
共 50 条
  • [21] The importance of the epithelial-mesenchymal transition in breast cancer
    Nathalie Sphyris
    Sendurai A. Mani
    Current Breast Cancer Reports, 2009, 1 (4) : 229 - 237
  • [22] Curcumin reverses irinotecan resistance in colon cancer cell by regulation of epithelial-mesenchymal transition
    Zhang, Chunhong
    Xu, Yangjie
    Wang, Haowen
    Li, Gang
    Yan, Han
    Fei, Zhenghua
    Xu, Yunsheng
    Li, Wenfeng
    ANTI-CANCER DRUGS, 2018, 29 (04) : 334 - 340
  • [23] Crosstalk between adipocytes and breast cancer promotes epithelial-mesenchymal transition
    Eun-Sol, Kim
    Seung, Koo Ja
    CANCER RESEARCH, 2017, 77
  • [24] Inhibition of Epithelial-mesenchymal Transition in Response to Treatment with Metformin and Y27632 in Breast Cancer Cell Lines
    Leonel, Camila
    Ferreira, Livia Carvalho
    Borin, Thaiz Ferraz
    Moschetta, Marina Gobbe
    Freitas, Gabriela Scavacini
    Haddad, Michel Raineri
    de Camargos Pinto Robles, Joao Antonio
    Pires de Campos Zuccari, Debora Aparecida
    ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2017, 17 (08) : 1113 - 1125
  • [25] Connexin 50 Inhibits Lens Epithelial Cells Migration and Epithelial-Mesenchymal Transition
    Ma, Bo
    Li, Zhen
    Wang, Guangyan
    Gu, Sumin
    Jiang, Jean
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023, 64 (08)
  • [26] Metformin regulates breast cancer stem cell ontogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status
    Vazquez-Martin, Alejandro
    Oliveras-Ferraros, Cristina
    Cuff, Silvia
    Del Barco, Sonia
    Martin-Castillo, Begona
    Menendez, Javier A.
    CELL CYCLE, 2010, 9 (18) : 3807 - 3814
  • [27] Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition
    Lin, Yuh-Charn
    Lee, Yi-Ching
    Li, Ling-Hui
    Cheng, Chien-Jui
    Yang, Ruey-Bing
    JOURNAL OF CELL SCIENCE, 2014, 127 (01) : 85 - 100
  • [28] Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition
    Lin, Yuh-Charn
    Lee, Yi-Ching
    Li, Ling-Hui
    Cheng, Chien-Jui
    Yang, Ruey-Bing
    CANCER RESEARCH, 2014, 74 (19)
  • [29] MicroRNA-218 inhibits the migration, epithelial-mesenchymal transition and cancer stem cell properties of prostate cancer cells
    Guan, Bing
    Mu, Lijun
    Zhang, Linlin
    Wang, Ke
    Tian, Juanhua
    Xu, Shan
    Wang, Xinyang
    He, Dalin
    Du, Yuefeng
    ONCOLOGY LETTERS, 2018, 16 (02) : 1821 - 1826
  • [30] Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway
    Qian-Qian Liu
    Ke Chen
    Qiao Ye
    Xiao-Hua Jiang
    Yun-Wei Sun
    Cancer Cell International, 16