Time to death predictors of HIV/AIDS infected patients on antiretroviral therapy in Ethiopia

被引:16
|
作者
Tadege M. [1 ]
机构
[1] Department of Statistics, Injibara University, Injibara Amhara
关键词
ART; HIV; Survival; TB;
D O I
10.1186/s13104-018-3863-y
中图分类号
学科分类号
摘要
Objective: The purpose of this study was to identify the major risk factors, which contributed to shortened survival time to death of HIV patients on antiretroviral therapy. Six-hundred HIV patients were included from two hospitals and six health centers record from January 2003 to December 2017. Kaplan-Meier and Cox proportional hazard model were implemented. Results: From the Kaplan-Meier, log-rank test result indicated that there was a significant difference between tuberculosis comorbidity (P =.000), occupation (P =.027), and WHO clinical stage (P =.012) on the survival experience of patients at 5% statistical significance level. From the Cox regression result, the risk of death for patients who lived with tuberculosis was about 2.872-fold times higher than those patients who were negative. Most of the HIV/AIDS patients on antiretroviral therapy were died in a short period due to tuberculosis comorbidity, began with lower amount of CD4, being underweight, merchant, and being on WHO clinical stage IV. © 2018 The Author(s).
引用
收藏
相关论文
共 50 条
  • [31] Predictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania
    Johannessen, Asgeir
    Naman, Ezra
    Ngowi, Bernard J.
    Sandvik, Leiv
    Matee, Mecky I.
    Aglen, Henry E.
    Gundersen, Svein G.
    Bruun, Johan N.
    BMC INFECTIOUS DISEASES, 2008, 8 (1)
  • [32] Durability and predictors of success of highly active antiretroviral therapy for ambulatory HIV-infected patients
    Palella, FJ
    Chmiel, JS
    Moorman, AC
    Holmberg, SD
    AIDS, 2002, 16 (12) : 1617 - 1626
  • [33] Frequency, predictors and outcome of viral rebounds in HIV-infected patients on suppressive antiretroviral therapy
    Tosti, A.
    Martinelli, L.
    Camanni, G.
    De Angelis, V.
    Sgrelli, A.
    Francisci, D.
    Baldelli, F.
    INFECTION, 2010, 38 : 58 - 59
  • [34] Predictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania
    Asgeir Johannessen
    Ezra Naman
    Bernard J Ngowi
    Leiv Sandvik
    Mecky I Matee
    Henry E Aglen
    Svein G Gundersen
    Johan N Bruun
    BMC Infectious Diseases, 8
  • [35] Predictors of virological response in HIV-infected patients to salvage antiretroviral therapy that includes nelfinavir
    Walmsley, SL
    Becker, MI
    Zhang, M
    Humar, A
    Harrigan, PR
    ANTIVIRAL THERAPY, 2001, 6 (01) : 47 - 54
  • [36] Prevalence and Predictors of Cytopenias in HIV-Infected Adults at Initiation of Antiretroviral Therapy in Mehal Meda Hospital, Central Ethiopia
    Fiseha, Temesgen
    Ebrahim, Hussen
    JOURNAL OF BLOOD MEDICINE, 2022, 13 : 201 - 211
  • [37] Neurocognitive Function in HIV Infected Patients on Antiretroviral Therapy
    Winston, Alan
    Arenas-Pinto, Alejandro
    Stoehr, Wolfgang
    Fisher, Martin
    Orkin, Chloe M.
    Aderogba, Kazeem
    De Burgh-Thomas, Andrew
    O'Farrell, Nigel
    Lacey, Charles J. N.
    Leen, Clifford
    Dunn, David
    Paton, Nicholas I.
    PLOS ONE, 2013, 8 (04):
  • [38] The use of combination antiretroviral therapy in HIV infected patients
    Holtzer, CD
    Roland, M
    ANNALS OF PHARMACOTHERAPY, 1999, 33 (02) : 198 - 209
  • [39] ANTIRETROVIRAL THERAPY IN HIV-INFECTED PATIENTS - UPDATE
    BARTLETT, JG
    INFECTIOUS DISEASES IN CLINICAL PRACTICE, 1994, 3 (05) : 340 - 344
  • [40] Effects of antiretroviral therapy on immunity in patients infected with HIV
    Feola, DJ
    Thornton, AC
    Garvy, BA
    CURRENT PHARMACEUTICAL DESIGN, 2006, 12 (09) : 1015 - 1022