Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents

被引:0
|
作者
Parvin Kumar
Kulbir Kadyan
Meenakshi Duhan
Jayant Sindhu
Vineeta Singh
Baljeet Singh Saharan
机构
[1] Kurukshetra University,Department of Chemistry
[2] S D (PG) College,Department of Microbiology
[3] National Institute of Malaria Research,undefined
[4] Kurukshetra University,undefined
来源
关键词
Antimalarial; DHP; Pyrazole; Conformational studies; Falcipain-2; Antimicrobial; Antifungal;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Design, synthesis and molecular docking of novel structural hybrids of substituted isatin based pyrazoline and thiadiazoline as antitumor agents
    Kiran Gangarapu
    Gouthami Thumma
    Sarangapani Manda
    Anvesh Jallapally
    Ravi Jarapula
    Sriram Rekulapally
    Medicinal Chemistry Research, 2017, 26 : 819 - 829
  • [22] Novel Dipeptides Bearing Sulfonamide as Antimalarial and Antitrypanosomal Agents: Synthesis and Molecular Docking
    Ekoh, Ogechi Chinelo
    Okoro, Uchechukwu
    Ugwu, David
    Ali, Rafat
    Okafor, Sunday
    Ugwuja, Daniel
    Attah, Solomon
    MEDICINAL CHEMISTRY, 2022, 18 (03) : 394 - 405
  • [23] Molecular hybrids integrated with imidazole and hydrazone structural motifs: Design, synthesis, biological evaluation, and molecular docking studies
    Tapera, Michael
    Saripinar, Emin
    Kekecmuhammed, Hueseyin
    Dogan, Murat
    Tuzun, Burak
    Kocyigit, Uemit M.
    Cetin, Feyza Nur
    JOURNAL OF MOLECULAR LIQUIDS, 2023, 391
  • [24] Synthesis and molecular docking studies of some novel antimicrobial benzamides
    Acar, Cemre
    Yalcin, Gozde
    Ertan-Bolelli, Tugba
    Onurdag, Fatma Kaynak
    Okten, Suzan
    Sener, Funda
    Yildiz, Ilkay
    BIOORGANIC CHEMISTRY, 2020, 94
  • [25] Synthesis, spectroscopic characterization, antimicrobial evaluation and molecular docking study of novel triazine-quinazolinone based hybrids
    Dinari, Mohammad
    Gharahi, Fateme
    Asadi, Parvin
    JOURNAL OF MOLECULAR STRUCTURE, 2018, 1156 : 43 - 50
  • [26] Synthesis, characterization, molecular docking studies and biological evaluation of some novel hybrids based on quinazolinone, benzofuran and imidazolium moieties as potential cytotoxic and antimicrobial agents
    Asadi, Parvin
    Khodarahmi, Ghadamali
    Jahanian-Najafabadi, Ali
    Saghaie, Lotfollah
    Hassanzadeh, Farshid
    IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2017, 20 (09) : 975 - 989
  • [27] Design, synthesis, and molecular docking of cysteine-based sulphonamide derivatives as antimicrobial agents
    Egbujor, Melford C.
    Okoro, Uchechukwu C.
    Okafor, Sunday N.
    Egu, Samuel A.
    Amasiatu, Ifeanyi S.
    Egwuatu, Pius, I
    Umeh, Odera R.
    Ibo, Eziafakaego M.
    RESEARCH IN PHARMACEUTICAL SCIENCES, 2022, 17 (01) : 99 - 110
  • [28] Design, synthesis, and molecular docking study of new piperazine derivative as potential antimicrobial agents
    Patil, Mahadev
    Poyil, Anurag Noonikara
    Joshi, Shrinivas D.
    Patil, Shivaputra A.
    Patil, Siddappa A.
    Bugarin, Alejandro
    BIOORGANIC CHEMISTRY, 2019, 92
  • [29] Synthesis, molecular docking and ADME studies of thiazole-thiazolidinedione hybrids as antimicrobial agents
    Alegaon, Shankar G.
    Venkatasubramanian, U.
    Alagawadi, K. R.
    Kumar, Dushyant
    Kavalapure, Rohini S.
    Ranade, Shriram D.
    Priya, Soundarya A.
    Jalalpure, Sunil S.
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2022, 40 (14): : 6211 - 6227
  • [30] Design, synthesis, molecular docking and in silico ADMET investigations of novel piperidine-bearing cinnamic acid hybrids as potent antimicrobial agents
    Ajayrajsinh R. Zala
    Dhanji P. Rajani
    Premlata Kumari
    Journal of the Iranian Chemical Society, 2023, 20 : 1843 - 1856