EZH2 variants differentially regulate polycomb repressive complex 2 in histone methylation and cell differentiation

被引:0
|
作者
Weipeng Mu
Joshua Starmer
Della Yee
Terry Magnuson
机构
[1] The University of North Carolina at Chapel Hill,Department of Genetics, and Lineberger Comprehensive Cancer Center
来源
关键词
Polycomb-group proteins; EZH2; Spermatogenesis; Alternative splicing; Histone methylation; Cell differentiation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] A Class of Protein-Coding RNAs Binds to Polycomb Repressive Complex 2 and Alters Histone Methylation
    Liao, Meijian
    Sun, Xiaolin
    Gao, Shoucui
    Zhang, Yaou
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [22] Substrate preferences of the EZH2 histone methyltransferase complex
    Martin, C
    Cao, R
    Zhang, Y
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (13) : 8365 - 8370
  • [23] Overexpression of polycomb repressive complex 2 key components EZH2/SUZ12/EED as an unfavorable prognostic marker in cholangiocarcinoma
    Wasenang, Wiphawan
    Puapairoj, Anucha
    Settasatian, Chatri
    Proungvitaya, Siriporn
    Limpaiboon, Temduang
    PATHOLOGY RESEARCH AND PRACTICE, 2019, 215 (07)
  • [24] EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit) gene expression is down-regulated in multiple sclerosis patients
    Malhotra, S.
    Tintore, M.
    Castillo, J.
    Montalban, X.
    Comabella, M.
    MULTIPLE SCLEROSIS JOURNAL, 2015, 21 : 451 - 452
  • [25] Erratum: The Polycomb group protein EZH2 directly controls DNA methylation
    Emmanuelle Viré
    Carmen Brenner
    Rachel Deplus
    Loïc Blanchon
    Mario Fraga
    Céline Didelot
    Lluis Morey
    Aleyde Van Eynde
    David Bernard
    Jean-Marie Vanderwinden
    Mathieu Bollen
    Manel Esteller
    Luciano Di Croce
    Yvan de Launoit
    François Fuks
    Nature, 2007, 446 : 824 - 824
  • [26] Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator
    Kim, Jung
    Lee, Yongik
    Lu, Xiaodong
    Song, Bing
    Fong, Ka-Wing
    Cao, Qi
    Licht, Jonathan D.
    Zhao, Jonathan C.
    Yu, Jindan
    CELL REPORTS, 2018, 25 (10): : 2808 - +
  • [27] The Polycomb Histone Lysine Methyltransferase EZH2 Controls Interstitial Cell of Cajal Populations by Regulating Stem Cell Differentiation and Self-Renewal
    Syed, Sabriya A.
    Lee, Jeong Heon
    Hayashi, Yujiro
    Gajdos, Gabriella B.
    Asuzu, David T.
    Nie, Jinfu J.
    Yan, Huihuang
    Rubin, Brian P.
    Urrutia, Raul
    Klein, Sabine
    Saur, Dieter
    Zhang, Zhiguo
    Ordog, Tamas
    GASTROENTEROLOGY, 2016, 150 (04) : S343 - S344
  • [28] Dense Chromatin Activates Polycomb Repressive Complex 2 to Regulate H3 Lysine 27 Methylation
    Yuan, Wen
    Wu, Tong
    Fu, Hang
    Dai, Chao
    Wu, Hui
    Liu, Nan
    Li, Xiang
    Xu, Mo
    Zhang, Zhuqiang
    Niu, Tianhui
    Han, Zhifu
    Chai, Jijie
    Zhou, Xianghong Jasmine
    Gao, Shaorong
    Zhu, Bing
    SCIENCE, 2012, 337 (6097) : 971 - 975
  • [29] In aggressive variants of non-Hodgkin lymphomas, Ezh2 is strongly expressed and polycomb repressive complex PRC1.4 dominates over PRC1.2
    Abd Al Kader, Lamia
    Oka, Takashi
    Takata, Katsuyoshi
    Sun, Xu
    Sato, Hiaki
    Murakami, Ichiro
    Toji, Tomohiro
    Manabe, Akihiro
    Kimura, Hiroshi
    Yoshino, Tadashi
    VIRCHOWS ARCHIV, 2013, 463 (05) : 697 - 711
  • [30] Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2
    Lee, Chul-Hwan
    Holder, Marlene
    Grau, Daniel
    Saldana-Meyer, Ricardo
    Yu, Jia-Ray
    Ganai, Rais Ahmad
    Zhang, Jenny
    Wang, Miao
    LeRoy, Gary
    Dobenecker, Marc-Werner
    Reinberg, Danny
    Armache, Karim-Jean
    MOLECULAR CELL, 2018, 70 (03) : 435 - +