The role of IL-37 in cancer

被引：0
|
作者：
Vivi A. Ding
Ziwen Zhu
Huaping Xiao
Mark R. Wakefield
Qian Bai
Yujiang Fang
机构：
[1] Des Moines University,Department of Microbiology, Immunology & Pathology
[2] University of Missouri School of Medicine,Department of Surgery
[3] The Affiliated Hospital of Xiangnan University,undefined
来源：
Medical Oncology | 2016年 / 33卷
关键词：
IL-37; Immunity; Cancer;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Interleukin 37 (IL-37) is a new member of the IL-1 family which all have a similar β-barrel structure. Since its discovery, IL-37 has been studied extensively in immunological field. It has been established that IL-37 possesses anti-inflammatory characteristics both in innate immune response as well as in acquired immune responses by downregulating pro-inflammatory molecules. This review will discuss the role of IL-37 in immunological processes and neoplastic pathogenesis.
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