PPP2R1B abolishes colorectal cancer liver metastasis and sensitizes Oxaliplatin by inhibiting MAPK/ERK signaling pathway

被引:0
|
作者
Wei Liu
Jingtong Tang
Wei Gao
Jian Sun
Gang Liu
Jianping Zhou
机构
[1] The First Hospital of China Medical University,Department of Gastrointestinal Surgery
[2] Daqing Oilfield General Hospital,Department of General Surgery
[3] Shenyang Medical Nutrition Clinical Medical Research Center,undefined
来源
关键词
PPP2R1B; Colorectal cancer; Liver metastasis; Oxaliplatin; p-ERK;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] Overexpression of ubiquitin carboxyl terminal hydrolase-L1 enhances multidrug resistance and invasion/metastasis in breast cancer by activating the MAPK/Erk signaling pathway
    Wang, Wenjuan
    Zou, Liping
    Zhou, Danmei
    Zhou, Zhongwen
    Tang, Feng
    Xu, Zude
    Liu, Xiuping
    MOLECULAR CARCINOGENESIS, 2016, 55 (09) : 1329 - 1342
  • [42] Nanoparticle (NP)-mediated APOC1 silencing to inhibit MAPK/ERK and NF-?B pathway and suppress breast cancer growth and metastasis
    Liu, Shaomin
    Zhang, Fengqian
    Liang, Yixia
    Wu, Guo
    Liu, Rong
    Li, Xiuling
    Saw, Phei Er
    Yang, Zhonghan
    SCIENCE CHINA-LIFE SCIENCES, 2023, 66 (11) : 2451 - 2465
  • [43] Nanoparticle (NP)-mediated APOC1 silencing to inhibit MAPK/ERK and NF-κB pathway and suppress breast cancer growth and metastasis
    Shaomin Liu
    Fengqian Zhang
    Yixia Liang
    Guo Wu
    Rong Liu
    Xiuling Li
    Phei Er Saw
    Zhonghan Yang
    Science China Life Sciences, 2023, 66 : 2451 - 2465
  • [44] Nanoparticle(NP)-mediated APOC1 silencing to inhibit MAPK/ERK and NF-κB pathway and suppress breast cancer growth and metastasis
    Shaomin Liu
    Fengqian Zhang
    Yixia Liang
    Guo Wu
    Rong Liu
    Xiuling Li
    Phei Er Saw
    Zhonghan Yang
    Science China(Life Sciences), 2023, 66 (11) : 2451 - 2465
  • [45] Nanoparticle(NP)-mediated APOC1 silencing to inhibit MAPK/ERK and NF-κB pathway and suppress breast cancer growth and metastasis
    Shaomin Liu
    Fengqian Zhang
    Yixia Liang
    Guo Wu
    Rong Liu
    Xiuling Li
    Phei Er Saw
    Zhonghan Yang
    Science China(Life Sciences) , 2023, (11) : 2451 - 2465
  • [46] Lunasin potentiates the effect of oxaliplatin preventing outgrowth of colon cancer metastasis, binds to α5β1 integrin and suppresses FAK/ERK/NF-κB signaling
    Dia, Vermont P.
    de Mejia, Elvira Gonzalez
    CANCER LETTERS, 2011, 313 (02) : 167 - 180
  • [47] miR-144 inhibits the IGF1R-ERK1/2 signaling pathway via NUDCD1 to suppress the proliferation and metastasis of colorectal cancer cells: a study based on bioinformatics and in vitro and in vivo verification
    Han, Bin
    Xu, Ke
    Feng, Dan
    Bai, Yang
    Liu, Yangqi
    Zhang, Yuanyuan
    Zhou, Liming
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2022, 148 (08) : 1903 - 1918
  • [48] miR-144 inhibits the IGF1R-ERK1/2 signaling pathway via NUDCD1 to suppress the proliferation and metastasis of colorectal cancer cells: a study based on bioinformatics and in vitro and in vivo verification
    Bin Han
    Ke Xu
    Dan Feng
    Yang Bai
    Yangqi Liu
    Yuanyuan Zhang
    Liming Zhou
    Journal of Cancer Research and Clinical Oncology, 2022, 148 : 1903 - 1918
  • [49] YWHAG promotes bladder cancer metastasis by regulating TMOD3 to activate ERK1/2 and JNK phosphorylation in the MAPK pathway
    Tian, Tai
    He, Shiming
    Hao, Han
    Guan, Bao
    Gong, Yanqing
    Fan, Jian
    Zhu, Zhenpeng
    Gao, Wenzhi
    Wu, Yucai
    Feng, Ninghan
    Wang, Aixiang
    Guo, Yuexian
    Li, Xuesong
    JOURNAL OF TRANSLATIONAL MEDICINE, 2024, 22 (01)
  • [50] HMGB1-mediated autophagy modulates sensitivity of colorectal cancer cells to oxaliplatin via MEK/ERK signaling pathway (vol 16, pg 511, 2015)
    Liu, Weijun
    Zhang, Zhenyong
    Zhang, Yongxue
    Chen, Xinju
    Guo, Shikui
    Lei, Yi
    Xu, Yu
    Ji, Chao
    Bi, Zhigang
    Wang, Kunhua
    CANCER BIOLOGY & THERAPY, 2015, 16 (10) : 1566 - 1566