Precise mapping of molecular and cellular brain changes in Alzheimer’s disease

被引:0
|
作者
机构
来源
Nature Neuroscience | 2023年 / 26卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
STARmap PLUS is a new spatial gene mapping method combined with histological staining. With STARmap PLUS, we created high-resolution, comprehensive maps of altered molecular pathways and reactive cells in a mouse model of Alzheimer’s disease. These maps enabled us to infer the trajectories of biological processes and cell states during disease progression.
引用
收藏
页码:371 / 372
页数:1
相关论文
共 50 条
  • [21] Mapping the Structural Brain Changes in Alzheimer's Disease: The Independent Contribution of Two Imaging Modalities
    Canu, Elisa
    McLaren, Donald G.
    Fitzgerald, Michele E.
    Bendlin, Barbara B.
    Zoccatelli, Giada
    Alessandrini, Franco
    Pizzini, Francesca B.
    Ricciardi, Giuseppe K.
    Beltramello, Alberto
    Johnson, Sterling C.
    Frisoni, Giovanni B.
    JOURNAL OF ALZHEIMERS DISEASE, 2011, 26 : 263 - 274
  • [22] Mapping progressive brain structural changes in early Alzheimer's disease and mild cognitive impairment
    Apostolova, Liana G.
    Thompson, Paul M.
    NEUROPSYCHOLOGIA, 2008, 46 (06) : 1597 - 1612
  • [23] Molecular and Cellular Foundations of Aging of the Brain: Anti-aging Strategies in Alzheimer's Disease
    Dziewa, Magdalena
    Zlotek, Magdalena
    Herbet, Mariola
    Piatkowska-Chmiel, Iwona
    CELLULAR AND MOLECULAR NEUROBIOLOGY, 2024, 44 (01)
  • [24] Retina and Brain Display Early and Differential Molecular and Cellular Changes in the 3xTg-AD Mouse Model of Alzheimer's Disease
    Rodrigues-Neves, Ana Catarina
    Carecho, Rafael
    Correia, Sonia Catarina
    Carvalho, Cristina
    Campos, Elisa Juliao
    Baptista, Filipa Isabel
    Moreira, Paula Isabel
    Ambrosio, Antonio Francisco
    MOLECULAR NEUROBIOLOGY, 2021, 58 (07) : 3043 - 3060
  • [25] Retina and Brain Display Early and Differential Molecular and Cellular Changes in the 3xTg-AD Mouse Model of Alzheimer’s Disease
    Ana Catarina Rodrigues-Neves
    Rafael Carecho
    Sónia Catarina Correia
    Cristina Carvalho
    Elisa Julião Campos
    Filipa Isabel Baptista
    Paula Isabel Moreira
    António Francisco Ambrósio
    Molecular Neurobiology, 2021, 58 : 3043 - 3060
  • [26] Brain cellular senescence in mouse models of Alzheimer's disease
    Dorigatti, Angela O.
    Riordan, Ruben
    Yu, Zhen
    Ross, Grace
    Wang, Rong
    Reynolds-Lallement, Nadjalisse
    Magnusson, Kathy
    Galvan, Veronica
    Perez, Viviana, I
    GEROSCIENCE, 2022, 44 (02) : 1157 - 1168
  • [27] BRAIN CELLULAR SENESCENCE IN MOUSE MODELS OF ALZHEIMER'S DISEASE
    Riordan, Ruben
    INNOVATION IN AGING, 2021, 5 : 929 - 929
  • [28] Brain cellular senescence in mouse models of Alzheimer’s disease
    Angela O. Dorigatti
    Ruben Riordan
    Zhen Yu
    Grace Ross
    Rong Wang
    Nadjalisse Reynolds-Lallement
    Kathy Magnusson
    Veronica Galvan
    Viviana I. Perez
    GeroScience, 2022, 44 : 1157 - 1168
  • [29] Structural changes in Alzheimer's disease brain microvessels
    Christov, Alexander
    Ottman, J.
    Hamdheydari, L.
    Grammas, Paula
    CURRENT ALZHEIMER RESEARCH, 2008, 5 (04) : 392 - 395
  • [30] Brain changes inpatients with Alzheimer's disease.
    Wallace, JR
    Vinters, HV
    JOURNAL OF INVESTIGATIVE MEDICINE, 2006, 54 (01) : S143 - S143