Precise mapping of molecular and cellular brain changes in Alzheimer’s disease

被引:0
|
作者
机构
来源
Nature Neuroscience | 2023年 / 26卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
STARmap PLUS is a new spatial gene mapping method combined with histological staining. With STARmap PLUS, we created high-resolution, comprehensive maps of altered molecular pathways and reactive cells in a mouse model of Alzheimer’s disease. These maps enabled us to infer the trajectories of biological processes and cell states during disease progression.
引用
收藏
页码:371 / 372
页数:1
相关论文
共 50 条
  • [1] Precise mapping of molecular and cellular brain changes in Alzheimer's disease
    Wang, Xiao
    Sheng, Morgan
    NATURE NEUROSCIENCE, 2023, 26 (03) : 371 - 372
  • [2] Mapping molecular changes in Huntington's disease brain
    Stoy, N.
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2008, 79 : A4 - A4
  • [4] Brain cholinesterases: II. The molecular and cellular basis of Alzheimer's disease
    Shen, Z
    MEDICAL HYPOTHESES, 2004, 63 (02) : 308 - 321
  • [5] Alzheimer's disease: Mapping the brain's decline
    Sarah C. P. Williams
    Nature, 2013, 502 : S84 - S85
  • [6] ALZHEIMER'S DISEASE Mapping the brain's decline
    Williams, Sarah C. P.
    NATURE, 2013, 502 (7473) : S84 - S85
  • [7] Alzheimer's disease : cellular and molecular aspects
    Octave, Jean-Noel
    Pierrot, Nathalie
    BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE, 2008, 192 (02): : 323 - 332
  • [8] Is statistical brain mapping a reliable tool to examine functional changes in Alzheimer's disease?
    Ishii, K
    Willoch, F
    Ficaro, EP
    Kuhl, DE
    Cross, DJ
    Drzezga, A
    Schwaiger, M
    Minoshima, S
    JOURNAL OF NUCLEAR MEDICINE, 2000, 41 (05) : 211P - 212P
  • [9] Cellular vulnerability in brain aging and Alzheimer's disease - Clinical correlates and molecular background
    Giannakopoulos, P
    Gold, G
    Michel, JP
    Bouras, C
    ANNALES DE MEDECINE INTERNE, 1998, 149 (04): : 187 - 191
  • [10] Magnetic Resonance Imaging to Detect Early Molecular and Cellular Changes in Alzheimer's Disease
    Knight, Michael J.
    McCann, Bryony
    Kauppinen, Risto A.
    Coulthard, Elizabeth J.
    FRONTIERS IN AGING NEUROSCIENCE, 2016, 8