CD19/CD20 dual-targeted chimeric antigen receptor-engineered natural killer cells exhibit improved cytotoxicity against acute lymphoblastic leukemia

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作者
Na Yang
Caili Zhang
Yingchun Zhang
Yuting Fan
Jing Zhang
Xiaojin Lin
Ting Guo
Yangzuo Gu
Jieheng Wu
Jianmei Gao
Xing Zhao
Zhixu He
机构
[1] Guizhou Medical University (GMU),Tissue Engineering and Stem Cell Experiment Center
[2] Guizhou Medical University,Department of Immunology, College of Basic Medical Sciences
[3] Guizhou Medical University,Department of Biology, School of Basic Medical Sciences
[4] the Affiliated Hospital of Guizhou Medical University,Department of Gynecology
[5] Sichuan University,State Key Laboratory of Biotherapy and Cancer Center
[6] Zunyi Medical University,School of Pharmacy
[7] Chinese Academy of Medical Sciences),Key Laboratory of Adult Stem Cell Translational Research
[8] the Affiliated Hospital of Zunyi Medical University,Department of Pediatrics
关键词
Chimeric antigen receptor; Natural killer cells; Dual targets; mRNA; Acute lymphoblastic leukemia;
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