A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer

被引：0
|
作者：
Cody J. Peer
Keith T. Schmidt
Jessica D. Kindrick
Joel R. Eisner
Victoria V. Brown
Edwina Baskin-Bey
Ravi Madan
William D. Figg
机构：
[1] National Cancer Institute,Clinical Pharmacology Program, CCR
[2] NIH,Genitourinary Malignancies Branch
[3] Innocrin Pharmaceuticals,undefined
[4] National Cancer Institute,undefined
[5] NIH,undefined
来源：
Cancer Chemotherapy and Pharmacology | 2019年 / 84卷
关键词：
Seviteronel CYP17 lyase; Population pharmacokinetics; Prostate cancer;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：759 / 770
页数：11
相关论文
共 50 条
  • [41] Androgen receptor mutations in patients with castration-resistant prostate cancer treated with apalutamide
    Rathkopf, D. E.
    Smith, M. R.
    Ryan, C. J.
    Berry, W. R.
    Shore, N. D.
    Liu, G.
    Higano, C. S.
    Alumkal, J. J.
    Hauke, R.
    Tutrone, R. F.
    Saleh, M.
    Maneval, E. Chow
    Thomas, S.
    Ricci, D. S.
    Yu, M. K.
    de Boer, C. J.
    Trinh, A.
    Kheoh, T.
    Bandekar, R.
    Scher, H. I.
    Antonarakis, E. S.
    ANNALS OF ONCOLOGY, 2017, 28 (09) : 2264 - 2271
  • [42] ODM-204, a novel dual inhibitor of CYP17A1 and androgen receptor for the treatment of castration-resistant prostate cancer.
    Kallio, Pekka
    Oksala, Riikka
    Moilanen, Anu
    Riikonen, Reetta
    Rummakko, Petteri
    Malmstrom, Chira
    Mustonen, Mika V. J.
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (02)
  • [43] ASN001, a novel CYP17 lyase inhibitor, in men with metastatic castration-resistant prostate cancer (mCRPC): Safety/tolerability and early activity in a multicenter phase 1/2 trial
    Rao, Niranjan Sathyanarayana
    Tolcher, Anthony W.
    Papadopoulos, Kyriakos P.
    Rasco, Drew W.
    Haas, Naomi B.
    Pantuck, Allan J.
    Denis, Louis J.
    Dreicer, Robert
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [44] Enzalutamide for patients with metastatic castration-resistant prostate cancer
    Ramadan, Wijdan H.
    Kabbara, Wissam K.
    Al Masri, Hiba S. Al Basiouni
    ONCOTARGETS AND THERAPY, 2015, 8 : 871 - 876
  • [45] Pharmacodynamic study of the oral hedgehog pathway inhibitor, vismodegib, in patients with metastatic castration-resistant prostate cancer
    Maughan, Benjamin L.
    Suzman, Daniel L.
    Luber, Brandon
    Wang, Hao
    Glavaris, Stephanie
    Hughes, Robert
    Sullivan, Rana
    Harb, Rana
    Boudadi, Karim
    Paller, Channing
    Eisenberger, Mario
    Demarzo, Angelo
    Ross, Ashely
    Antonarakis, Emmanuel S.
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2016, 78 (06) : 1297 - 1304
  • [46] Pharmacodynamic study of the oral hedgehog pathway inhibitor, vismodegib, in patients with metastatic castration-resistant prostate cancer
    Benjamin L. Maughan
    Daniel L. Suzman
    Brandon Luber
    Hao Wang
    Stephanie Glavaris
    Robert Hughes
    Rana Sullivan
    Rana Harb
    Karim Boudadi
    Channing Paller
    Mario Eisenberger
    Angelo Demarzo
    Ashely Ross
    Emmanuel S. Antonarakis
    Cancer Chemotherapy and Pharmacology, 2016, 78 : 1297 - 1304
  • [47] Androgen Receptor and Beyond, Targeting Androgen Signaling in Castration-Resistant Prostate Cancer
    Reichert, Zachery R.
    Hussain, Maha
    CANCER JOURNAL, 2016, 22 (05): : 326 - 329
  • [48] CYP17A1 inhibitors in castration-resistant prostate cancer
    Gomez, Lissette
    Kovac, Jason R.
    Lamb, Dolores J.
    STEROIDS, 2015, 95 : 80 - 87
  • [49] Genomic Profiling of Metastatic Castration-Resistant Prostate Cancer Samples Resistant to Androgen Receptor Pathway Inhibitors
    Menssouri, Naoual
    Poiraudeau, Loic
    Helissey, Carole
    Bigot, Ludovic
    Sabio, Jonathan
    Ibrahim, Tony
    Pobel, Cedric
    Nicotra, Claudio
    Ngo-Camus, Maud
    Lacroix, Ludovic
    Rouleau, Etienne
    Tselikas, Lambros
    Chauchereau, Anne
    Blanc-Durand, Felix
    Bernard-Tessier, Alice
    Patrikidou, Anna
    Naoun, Natacha
    Flippot, Ronan
    Colomba, Emeline
    Fuerea, Alina
    Albiges, Laurence
    Lavaud, Pernelle
    van de Wiel, Paul
    den Biezen, Eveline
    Wesseling-Rozendaal, Yvonne
    Ponce, Santiago
    Michiels, Stefan
    Massard, Christophe
    Gautheret, Daniel
    Barlesi, Fabrice
    Andre, Fabrice
    Besse, Benjamin
    Scoazec, Jean-Yves
    Friboulet, Luc
    Fizazi, Karim
    Loriot, Yohann
    CLINICAL CANCER RESEARCH, 2023, 29 (21) : 4504 - 4517
  • [50] Targeting the Adrenal Gland in Castration-Resistant Prostate Cancer: A Case for Orteronel, a Selective CYP-17 17,20-Lyase Inhibitor
    Hui Zhu
    Jorge A. Garcia
    Current Oncology Reports, 2013, 15 : 105 - 112
12345