Gender Differences in the Oral Pharmacokinetics of Fluconazole

被引:0
|
作者
Miriam del C. Carrasco-Portugal
Francisco J. Flores-Murrieta
机构
[1] Unidad de Farmacología Clínica y Experimental,Instituto Nacional de Enfermedades Respiratorias, Secretaría de Salud
[2] Sección de Estudios de Posgrado e Investigatión,Escuela Superior de Medicina del Instituto Politécnico Nacional
来源
关键词
Fluconazole; Total Body Water; Systemic Mycosis; Triazole Derivative; Reach Maximum Plasma Concentration;
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中图分类号
学科分类号
摘要
Background and objective: Fluconazole is a triazole derivative widely used for the treatment of mycoses. It has been established that several factors are able to modify its pharmacokinetics, including the bodyweight of the patient; however, there is controversy about the influence of gender on the pharmacokinetics of fluconazole. In order to clarify this controversy we decided to evaluate the pharmacokinetics of fluconazole in males and females.
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页码:851 / 855
页数:4
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