Stability studies on nifedipine tablets using thermogravimetry and differential scanning calorimetry

被引：0
|
作者：
R. O. C. Filho
P. I. B. M. Franco
E. C. Conceição
M. I. G. Leles
机构：
[1] Univ. Federal de Goiás-UFG Campus Samambaia,LAMES
[2] Univ. Federal de Goiás-UFG,Laboratório de Métodos de Extração e Separação, Instituto de Química
来源：
Journal of Thermal Analysis and Calorimetry | 2008年 / 93卷
关键词：
differential scanning calorimetry (DSC); nifedipine; stability studies; thermogravimetry (TG);
D O I：
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中图分类号：
学科分类号：
摘要：
A formulation of nifedipine tablets was prepared in the present research. The tablets were conditioned in amber-colored glass containers and placed in a climatized room at 40°C and relative humidity of 75% for 180 days. Differential scanning calorimetry (DSC) and thermogravimetry (TG) were used in order to evaluate the thermal properties of nifedipine, the excipients and two well-known nifedipine degradation products. The results demonstrated that there is no evidence on the interaction between nifedipine and excipients, or degradation products.
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页码：381 / 385
页数：4
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