Cancer stem cell immunoediting by IFNγ

被引：0
|
作者：
Claudia Galassi
Lorenzo Galluzzi
机构：
[1] Weill Cornell Medical College,Department of Radiation Oncology
[2] Sandra and Edward Meyer Cancer Center,undefined
[3] Caryl and Israel Englander Institute for Precision Medicine,undefined
来源：
Cell Death & Disease | / 14卷
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摘要：
The secretion of interferon gamma (IFNG, best known as IFNγ) by immune effector cells generally mediates potent anticancer effects. Recent data from Beziaud et al. demonstrate that—at least in some circumstances—IFNγ can edit the breast cancer microenvironment to promote stemness, disease progression and resistance to (immuno)therapy.
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