Dipentaerythritol in the Synthesis of New-Type Phospholipids

The first representatives of phospholipids of new types were synthesized on the basis of dipentaerythritol, 2,2′-[oxybis(methylen)]bis(hydroxymethyl))-1,3-propandiol. The starting polyol was phosphorylated with hexaethylphosphoric triamide to biphosphite, which was converted into thio- and selenophosphates by treatment with sulfur or selenium. The phosphoacetals were transformed into thio- and selenoanalogues of phospholipids by direct acylation with higher fatty acid chlorides.