Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signaling

被引:0
|
作者
Michaela Lang
Melanie Borgmann
Georg Oberhuber
Rayko Evstatiev
Kristine Jimenez
Kyle W Dammann
Manuela Jambrich
Vineeta Khare
Christoph Campregher
Robin Ristl
Christoph Gasche
机构
[1] Medical University of Vienna,Department of Medicine III, Division of Gastroenterology and Hepatology
[2] Medical University of Vienna,Christian Doppler Laboratory for Molecular Cancer Chemoprevention
[3] Pathology Ueberlingen,Center for Medical Statistics, Informatics, and Intelligent Systems, Section for Medical Statistics
[4] Medical University of Vienna,undefined
来源
关键词
Thymoquinone; Chemoprevention; Colon cancer; Familial adenomatous polyposis;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation
    Fuertes, Guillem
    del Valle-Perez, Beatriz
    Pastor, Javier
    Andrades, Evelyn
    Pena, Raul
    de Herreros, Antonio Garcia
    Dunach, Mireia
    EMBO REPORTS, 2023, 24 (04)
  • [32] Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice
    Leibing, Thomas
    Geraud, Cyrill
    Augustin, Iris
    Boutros, Michael
    Augustin, Hellmut G.
    Okun, Juergen G.
    Langhans, Claus-Dieter
    Zierow, Johanna
    Wohlfeil, Sebastian A.
    Olsavszky, Victor
    Schledzewski, Kai
    Goerdt, Sergij
    Koch, Philipp-Sebastian
    HEPATOLOGY, 2018, 68 (02) : 707 - 722
  • [33] Blockade of Wnt Signaling Inhibits Angiogenesis and Tumor Growth in Hepatocellular Carcinoma
    Hu, Jie
    Dong, Aiwen
    Fernandez-Ruiz, Veronica
    Shan, Juanjuan
    Kawa, Milosz
    Martinez-Anso, Eduardo
    Prieto, Jesus
    Qian, Cheng
    CANCER RESEARCH, 2009, 69 (17) : 6951 - 6959
  • [34] Effect of vitamin E δ-tocotrienol and aspirin on Wnt signaling in human colon cancer stem cells and in adenoma development in APCmin/+ mice
    Husain, Kazim
    Coppola, Domenico
    Yang, Chung S.
    Malafa, Mokenge P.
    CARCINOGENESIS, 2024, 45 (12) : 881 - 892
  • [35] Inhibition of Notch signaling attenuates pituitary adenoma growth in Nude mice
    Zubeldia-Brenner, Lautaro
    De Winne, Catalina
    Perrone, Sofia
    Rodriguez-Segui, Santiago A.
    Willems, Christophe
    Maria Ornstein, Ana
    Lacau-Mengido, Isabel
    Vankelecom, Hugo
    Cristina, Carolina
    Becu-Villalobos, Damasia
    ENDOCRINE-RELATED CANCER, 2019, 26 (01) : 13 - 29
  • [36] Genetic Ablation of TNF-α Attenuates High Fat Diet-induced Obesity Potentially via Diminishing Wnt-signaling and Determinant Genes of Adipogenesis
    Li, Jinchao
    Frederick, Armina-Lyn
    Kim, Young-Cheul
    Wood, Richard J.
    Liu, Zhenhua
    FASEB JOURNAL, 2016, 30
  • [37] The Absence of LPA2 Attenuates Tumor Formation in Both An Animal Model of Colitis-Associated Cancer and APCMIN/+ Mice
    Lin, Songbai
    Ghaleb, Amr
    Shim, Hyunsuk
    Yang, Vincent W.
    Chun, Jerold
    Yun, C. Chris
    GASTROENTEROLOGY, 2009, 136 (05) : A115 - A115
  • [38] Cooperative effects of mushroom polysaccharides and herbal saponins on tumor growth and gut microenvironment in ApcMin/ plus mice
    Li, Xiao-ang
    Huang, Guoxin Huang
    Khan, Imran
    Xia, Wen-rui
    Leong, Wai Kit
    Hsiao, W. L. Wendy
    CANCER RESEARCH, 2018, 78 (13)
  • [39] SOX30 Inhibits Tumor Metastasis through Attenuating Wnt-Signaling via Transcriptional and Posttranslational Regulation of β-Catenin in Lung Cancer
    Han, Fei
    Liu, Wen-bin
    Shi, Xiao-yan
    Yang, Jun-tang
    Zhang, Xi
    Li, Zhi-ming
    Jiang, Xiao
    Yin, Li
    Li, Jian-jun
    Huang, Chuan-shu
    Cao, Jia
    Liu, Jin-yi
    EBIOMEDICINE, 2018, 31 : 253 - 266
  • [40] Inactivation of Wnt signaling in medulloblastomas -: future therapeutic strategies to interfere with tumor growth
    Koch, A
    Hartmann, W
    Waha, A
    Rutkowski, S
    Sörensen, N
    Berthold, F
    Pietsch, T
    KLINISCHE PADIATRIE, 2006, 218 (03): : 189 - 189