An Investigation of Instability in Dried Blood Spot Samples for Pharmacokinetic Sampling in Phase 3 Trials of Verubecestat

被引:0
|
作者
Melanie Anderson
Marissa F. Dockendorf
Ian McIntosh
Iris Xie
Sheila Breidinger
Dongfang Meng
Sumei Ren
Wendy Zhong
Li Zhang
Brad Roadcap
Kevin P. Bateman
Julie Stone
Eric Woolf
机构
[1] Merck & Co.,Pharmacokinetics, Pharmacodynamics and Drug Metabolism
[2] Inc.,Process Chemistry
[3] Merck & Co.,SM PR&D
[4] Inc.,Analytical Research & Development
[5] Merck & Co.,undefined
[6] Inc.,undefined
[7] Merck & Co.,undefined
[8] Inc.,undefined
来源
关键词
Dried blood spots; Pharmacokinetic sampling; Stability; Verubecestat;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] DELIVERING NEONATAL DRUGS RESEARCH: ACCEPTABILITY OF DRIED BLOOD SPOT SAMPLING FOR PHARMACOKINETIC RESEARCH IN PRETERM INFANTS
    Soto, C.
    Terry, H. K.
    Pandya, H.
    Field, D. J.
    Kairamkonda, V.
    Spooner, N.
    Boyle, E. M.
    [J]. INTENSIVE CARE MEDICINE, 2011, 37 : S411 - S411
  • [22] Evaluation of dried blood spot technique for pharmacokinetic study of hydrochlorothiazide and comparison of human plasma versus dried blood spot
    Kumar, P. Pavan
    Murthy, T. E. G. K.
    [J]. JOURNAL OF YOUNG PHARMACISTS, 2014, 6 (02) : 44 - 49
  • [23] The dried blood spot sampling method in the laboratory medicine
    Andrlova, L.
    Kandar, R.
    [J]. BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, 2019, 120 (03): : 223 - 234
  • [24] Applying dried blood spot sampling with LCMS quantification in the clinical development phase of tasquinimod
    Svensson, Leif D.
    Sennbro, Carl-Johan
    Svanstrom, Camilla
    Hansson, Gunnar P.
    [J]. BIOANALYSIS, 2015, 7 (02) : 179 - 191
  • [25] Overcoming challenges with the dilution of dried blood spot samples
    不详
    [J]. BIOANALYSIS, 2011, 3 (10) : 1054 - 1054
  • [26] Quantification of multiple elements in dried blood spot samples
    Pedersen, Lise
    Andersen-Ranberg, Karen
    Hollergaard, Mads
    Nybo, Mads
    [J]. CLINICAL BIOCHEMISTRY, 2017, 50 (12) : 703 - 709
  • [27] Patterned Dried Blood Spot Cards for the Improved Sampling of Whole Blood
    Baillargeon, Keith R.
    Brooks, Jessica C.
    Miljanic, Philip R.
    Mace, Charles R.
    [J]. ACS MEASUREMENT SCIENCE AU, 2021, 2 (01): : 31 - 38
  • [28] Dried blood spot versus venous blood sampling for phenylalanine and tyrosine
    van Vliet, Kimber
    van Ginkel, Wiggert G.
    van Dam, Esther
    de Blaauw, Pim
    Koehorst, Martijn
    Kingma, Hermi A.
    van Spronsen, Francjan J.
    Heiner-Fokkema, M. Rebecca
    [J]. ORPHANET JOURNAL OF RARE DISEASES, 2020, 15 (01)
  • [29] Dried blood spot versus venous blood sampling for phenylalanine and tyrosine
    Kimber van Vliet
    Wiggert G. van Ginkel
    Esther van Dam
    Pim de Blaauw
    Martijn Koehorst
    Hermi A. Kingma
    Francjan J. van Spronsen
    M. Rebecca Heiner-Fokkema
    [J]. Orphanet Journal of Rare Diseases, 15
  • [30] Dried Blood Spot Sampling - A New Approach for Whole Blood Analysis
    Hilder, Emily F.
    [J]. AUSTRALIAN JOURNAL OF CHEMISTRY, 2011, 64 (06) : 843 - 843