AMG-510 and cisplatin combination increases antitumor effect in lung adenocarcinoma with mutation of KRAS G12C: a preclinical and translational research

被引：0
|
作者：
Lei-Lei Wu
Wen-Mei Jiang
Zhi-Yuan Liu
Yi-Yi Zhang
Jia-Yi Qian
Yu’e Liu
Yang-Yu Huang
Kun Li
Zhi-Xin Li
Guo-Wei Ma
Dong Xie
机构：
[1] Tongji University,Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine
[2] Sun Yat-sen University Cancer Center,State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine
[3] Tongji University,School of Medicine
[4] The University of Manchester,Faculty of Biology, Medicine and Health, School of Biological Sciences
来源：
Discover Oncology | / 14卷
关键词：
KRAS G12C mutation; AMG-510; Cisplatin; In vivo; Translational medicine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] AMG-510 and cisplatin combination increases antitumor effect in lung adenocarcinoma with mutation of KRAS G12C: a preclinical and translational research
    Wu, Lei-Lei
    Jiang, Wen-Mei
    Liu, Zhi-Yuan
    Zhang, Yi-Yi
    Qian, Jia-Yi
    Liu, Yu'e
    Huang, Yang-Yu
    Li, Kun
    Li, Zhi-Xin
    Ma, Guo-Wei
    Xie, Dong
    DISCOVER ONCOLOGY, 2023, 14 (01)
  • [2] Targeting KRAS G12C mutation in lung adenocarcinoma
    Rohatgi, Anjali
    Govindan, Ramaswamy
    LUNG CANCER, 2022, 165 : 28 - 33
  • [3] 针对KRAS G12C的首个抗肿瘤药物——AMG 510
    王灵智
    于芳
    何宇鹏
    李行舟
    临床药物治疗杂志, 2020, 18 (05) : 31 - 34
  • [4] The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity
    Canon, Jude
    Rex, Karen
    Saiki, Anne Y.
    Mohr, Christopher
    Cooke, Keegan
    Bagal, Dhanashri
    Gaida, Kevin
    Holt, Tyler
    Knutson, Charles G.
    Koppada, Neelima
    Lanman, Brian A.
    Werner, Jonathan
    Rapaport, Aaron S.
    San Miguel, Tisha
    Ortiz, Roberto
    Osgood, Tao
    Sun, Ji-Rong
    Zhu, Xiaochun
    McCarter, John D.
    Volak, Laurie P.
    Houk, Brett E.
    Fakih, Marwan G.
    O'Neil, Bert H.
    Price, Timothy J.
    Falchook, Gerald S.
    Desai, Jayesh
    Kuo, James
    Govindan, Ramaswamy
    Hong, David S.
    Ouyang, Wenjun
    Henary, Haby
    Arvedson, Tara
    Cee, Victor J.
    Lipford, J. Russell
    NATURE, 2019, 575 (7781) : 217 - +
  • [5] The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity
    Jude Canon
    Karen Rex
    Anne Y. Saiki
    Christopher Mohr
    Keegan Cooke
    Dhanashri Bagal
    Kevin Gaida
    Tyler Holt
    Charles G. Knutson
    Neelima Koppada
    Brian A. Lanman
    Jonathan Werner
    Aaron S. Rapaport
    Tisha San Miguel
    Roberto Ortiz
    Tao Osgood
    Ji-Rong Sun
    Xiaochun Zhu
    John D. McCarter
    Laurie P. Volak
    Brett E. Houk
    Marwan G. Fakih
    Bert H. O’Neil
    Timothy J. Price
    Gerald S. Falchook
    Jayesh Desai
    James Kuo
    Ramaswamy Govindan
    David S. Hong
    Wenjun Ouyang
    Haby Henary
    Tara Arvedson
    Victor J. Cee
    J. Russell Lipford
    Nature, 2019, 575 : 217 - 223
  • [6] The Research Progress of Direct KRAS G12C Mutation Inhibitors
    Yang, Ai
    Li, Min
    Fang, Mingzhi
    PATHOLOGY & ONCOLOGY RESEARCH, 2021, 27
  • [7] Prognostic value of KRAS G12C mutation in lung adenocarcinoma stratified by stages and radiological features
    Cao, Hang
    Ma, Zelin
    Li, Yuan
    Zhang, Yang
    Chen, Haiquan
    JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2023, 166 (06): : E479 - E499
  • [8] Elucidating the mechanisms of acquired resistance to AMG510 in cancer models harboring KRAS G12C mutations
    Ni, Ting
    Huo, Tongxin
    Zhang, Yawen
    Wang, Jingjing
    Liu, Gaoxiang
    Shi, Wenting
    Gu, Qingyang
    CANCER RESEARCH, 2024, 84 (06)
  • [9] KRAS(G12C)-AMG 510 interaction dynamics revealed by all-atom molecular dynamics simulations
    Pantsar, Tatu
    SCIENTIFIC REPORTS, 2020, 10 (01)
  • [10] Phase I study of AMG 510, a novel molecule targeting KRAS G12C mutant solid tumours
    Govindan, R.
    Fakih, M. G.
    Price, T. J.
    Falchook, G. S.
    Desai, J.
    Kuo, J. C.
    Strickler, J. H.
    Krauss, J. C.
    Li, B. T.
    Denlinger, C. S.
    Durm, G.
    Ngang, J.
    Henary, H.
    Ngarmchamnanrith, G.
    Rasmussen, E.
    Morrow, P. K.
    Hong, D. S.
    ANNALS OF ONCOLOGY, 2019, 30 : 163 - +
12345