Autosomal-STR based genetic structure of Chinese Xibe ethnic group and its relationships to various groups

被引：0
|
作者：
Haotian Meng
Yuxin Guo
Qian Dong
Guang Yang
Jiangwei Yan
Jianfeng Shi
Bofeng Zhu
机构：
[1] Xi’an Jiaotong University,Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology
[2] Xi’an Jiaotong University,Clinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, Hospital of Stomatology
[3] Xi’an Jiaotong University,Research Center of Stomatology, Stomatological Hospital
[4] Loma Linda University Medical Center,Department of Pathology and Laboratory Medicine
[5] Chinese Academy of Sciences,Key Laboratory of Genome Sciences, Beijing Institute of Genomics
来源：
International Journal of Legal Medicine | 2016年 / 130卷
关键词：
Genetic polymorphism; Interpopulation comparison; Xibe ethnic group; Autosomal-STR;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The short tandem repeat (STR) is one of the most widely used genetic makers in forensic DNA labs worldwide. In the present study, we investigated the genetic structure of 19 autosomal STRs and 1 sex-determining locus (amelogenin) in the Xibe ethnic group in China, as well as its relationships to other groups. One hundred and ninety-five alleles were detected in 222 unrelated healthy Xibe individuals. The values of combined power of discrimination and probability of exclusion of all 19 STR loci were 0.99999999999999999999996912 and 0.999999997538, respectively. Principal component analysis revealed relationships between the Xibe group and other groups, which showed a relatively close genetic relationship between the Xibe and Korean groups.
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页码：1501 / 1503
页数：2
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