Vaginal Prostate Specific Antigen (PSA) Is a Useful Biomarker of Semen Exposure Among HIV-Infected Ugandan Women

被引:0
|
作者
Sarah E. Woolf-King
Winnie Muyindike
Marcia M. Hobbs
Adrine Kusasira
Robin Fatch
Nneka Emenyonu
Mallory O. Johnson
Judith A. Hahn
机构
[1] University of California,Department of Medicine
[2] San Francisco (UCSF),School of Medicine
[3] Mbarara University of Science and Technology (MUST),undefined
[4] University of North Carolina at Chapel Hill,undefined
来源
AIDS and Behavior | 2017年 / 21卷
关键词
Self-report; Condom use; Biomarker; Prostate specific antigen; HIV;
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摘要
The practical feasibility of using prostate specific antigen (PSA) as a biomarker of semen exposure was examined among HIV-infected Ugandan women. Vaginal fluids were obtained with self-collected swabs and a qualitative rapid test (ABAcard®p30) was used to detect PSA. Trained laboratory technicians processed samples on-site and positive PSA tests were compared to self-reported unprotected vaginal sex (UVS) in the last 48 h. A total of 77 women submitted 126 samples for PSA testing at up to three study visits. Of these samples, 31 % (n = 39/126) were PSA positive, and 64 % (n = 25/39) of the positive PSA samples were accompanied by self-report of no UVS at the study visit the PSA was collected. There were no reported difficulties with specimen collection, storage, or processing. These findings provide preliminary data on high levels of misreported UVS among HIV-infected Ugandan women using practically feasible methods for PSA collection and processing.
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页码:2141 / 2146
页数:5
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