Screening of antimicrobial activities in red, green and brown macroalgae from Gran Canaria (Canary Islands, Spain)

被引:0
|
作者
Val A.G.D. [1 ]
Platas G. [1 ]
Basilio A. [1 ]
Cabello A. [1 ]
Gorrochategui J. [1 ]
Suay I. [1 ]
Vicente F. [1 ]
Portillo E. [2 ]
Río M.J.D. [2 ]
Reina G.G. [3 ]
Peláez F. [1 ]
机构
[1] Center for Basic Research - Natural Products Drug Discovery, Merck Research Laboratories, Merck Sharp and Dohme de España, 28027 Madrid
[2] Center for Applied Biological Research, Canary Islands Technological Institute, Las Palmas de Gran Canaria
[3] Institute for Applied Algology, Las Palmas de Gran Canaria University, Las Palmas, Telde
关键词
Antibacterial compounds; Antifungal compounds; Antimicrobial screening; Bioactivity; Seaweeds;
D O I
10.1007/s101230100006
中图分类号
学科分类号
摘要
Extracts from 44 species of seaweed from Gran Canada (Canary Islands, Spain) were screened for the production of antibacterial and antifungal compounds against a panel of Gram-negative and Grampositive bacteria, mycobacteria, yeasts and fungi. A total of 28 species displayed antibacterial activity, of which six also showed antifungal activity. Asparagopsis taxifonnis and Cynwpolia barbata were the species with the strongest activities against the broadest spectrum of target microorganisms. All the species with antibacterial activity were active against Gram-positive bacteria, whereas only two species, A. taxiformis and Osimmdea liybrida, were active against mycobacteria. The production of secondary metabolites with antimicrobial activities by the macroalgae was also studied under different conditions, although no common trend for bioactivity was observed. © Springer-Verlag and SEM 2001.
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页码:35 / 40
页数:5
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