A Phase 1 dose-escalation study to evaluate safety, pharmacokinetics and pharmacodynamics of AsiDNA, a first-in-class DNA repair inhibitor, administered intravenously in patients with advanced solid tumours

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作者
Christophe Le Tourneau
Jean-Pierre Delord
Nuria Kotecki
Edith Borcoman
Carlos Gomez-Roca
Ségolène Hescot
Christiane Jungels
Anne Vincent-Salomon
Vincent Cockenpot
Lauriane Eberst
Audrey Molé
Wael Jdey
Françoise Bono
Véronique Trochon-Joseph
Hélène Toussaint
Christelle Zandanel
Olga Adamiec
Olivier de Beaumont
Philippe Alexandre Cassier
机构
[1] Institut Curie,Department of Drug Development and Innovation (D3i)
[2] IUCT-Oncopole,Institut Claudius Régaud
[3] Institut Jules Bordet,Medical Oncology Clinic
[4] Institut Curie,Department of Tumor Biology
[5] Centre Léon Bérard,Medical Oncology
[6] Onxeo,Clinical Department
[7] Onxeo,Scientific Department
来源
British Journal of Cancer | 2020年 / 123卷
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页码:1481 / 1489
页数:8
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