Non-canonical cholinergic anti-inflammatory pathway in IBD

被引：0
|
作者：
Alan de Araujo
Guillaume de Lartigue
机构：
[1] University of Florida,Department of Pharmacodynamics, College of Pharmacy
[2] University of Florida,Center for Integrative Cardiovascular and Metabolic Disease
来源：
Nature Reviews Gastroenterology & Hepatology | 2020年 / 17卷
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摘要：
Vagus nerve stimulation has shown promise in treating inflammatory bowel disease. A new study identifies a hepatic vagal branch pathway necessary to maintain colonic immune cell homeostasis in experimental colitis, challenging the dogma that an anti-inflammatory reflex requires an intact spleen and that α7-nicotinic receptor agonists are a panacea for inflammatory conditions.
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页码：651 / 652
页数：1
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