Endoplasmic reticulum: Membrane contact sites

被引：0
|
作者：
Velikanov G.A. [1 ]
机构：
[1] Kazan Institute of Biochemistry and Biophysics, Kazan Research Center of the Russian Academy of Sciences, Kazan
来源：
Cell and Tissue Biology | 2013年 / 7卷 / 6期
关键词：
endoplasmic reticulum; functions; membrane contact sites;
D O I：
10.1134/S1990519X13060138
中图分类号：
学科分类号：
摘要：
This paper presents a review of modern data on the functional designation of membrane contact sites (MCSs) of endoplasmic reticulum. Problems of traffic of lipids and calcium in are discussed. It is to be emphasized that the function of MCSs is not yet clear, while the mechanism providing contact of two membranes (the problem of "anchors") remains poorly studied. Data are discussed that testify in favor of MCSs being able to participate both in selective traffic of lipids and in free diffusion of any small molecule (apparently, up to 1.5 kDa) and ions between cell compartments that are in contact. © 2013 Pleiades Publishing, Ltd.
引用
收藏
页码：504 / 511
页数：7
相关论文
共 50 条
  • [41] A membrane protein enriched in endoplasmic reticulum exit sites interacts with COPII
    Tang, BL
    Ong, YS
    Huang, B
    Wei, S
    Wong, ET
    Qi, R
    Horstmann, H
    Hong, W
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (43) : 40008 - 40017
  • [42] Arabidopsis SYT1 maintains stability of cortical endoplasmic reticulum networks and VAP27-1-enriched endoplasmic reticulum-plasma membrane contact sites
    Siao, Wei
    Wang, Pengwei
    Voigt, Boris
    Hussey, Patrick J.
    Baluska, Frantisek
    JOURNAL OF EXPERIMENTAL BOTANY, 2016, 67 (21) : 6161 - 6171
  • [43] The Machinery at Endoplasmic Reticulum-Plasma Membrane Contact Sites Contributes to Spatial Regulation of Multiple Legionella Effector Proteins
    Hubber, Andree
    Arasaki, Kohei
    Nakatsu, Fubito
    Hardiman, Camille
    Lambright, David
    De Camilli, Pietro
    Nagai, Hiroki
    Roy, Craig R.
    PLOS PATHOGENS, 2014, 10 (07)
  • [44] Extended-Synaptotagmins are endoplasmic reticulum (ER) proteins that function as tethers at ER-plasma membrane contact sites
    Giordano, F.
    Saheki, Y.
    Idevall-Hagren, O.
    Borgese, N.
    De Camilli, P.
    MOLECULAR BIOLOGY OF THE CELL, 2012, 23
  • [45] Editorial: the role of mitochondrial endoplasmic reticulum contact sites in human health and disease
    Katti, Prasanna
    Love-Rutledge, Sharifa
    Murray, Sandra. A. A.
    Hinton Jr, Antentor
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2023, 10
  • [46] Unbiased screenings illuminate regulators of mitochondria-endoplasmic reticulum contact sites
    Scorrano, L.
    FEBS OPEN BIO, 2024, 14 : 25 - 25
  • [47] Three-dimensional architecture of extended synaptotagmin-mediated endoplasmic reticulum-plasma membrane contact sites
    Fernandez-Busnadiego, Ruben
    Saheki, Yasunori
    De Camilli, Pietro
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (16) : E2004 - E2013
  • [48] A close-up view of membrane contact sites between the endoplasmic reticulum and the endolysosomal system: From yeast to man
    Hoenscher, Carina
    Ungermann, Christian
    CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2014, 49 (03) : 262 - 268
  • [49] A conserved mechanism targets lipid binding proteins to membrane contact sites between the endoplasmic reticulum and other organelles.
    Loewen, CJR
    Roy, A
    Levine, TP
    YEAST, 2003, 20 : S39 - S39
  • [50] Mitochondria-Endoplasmic Reticulum Contact Sites Mediate Innate Immune Responses
    Misawa, Takuma
    Takahama, Michihiro
    Saitoh, Tatsuya
    ORGANELLE CONTACT SITES: FROM MOLECULAR MECHANISM TO DISEASE, 2017, 997 : 187 - 197
12345