STING agonist therapy in combination with PD-1 immune checkpoint blockade enhances response to carboplatin chemotherapy in high-grade serous ovarian cancer

被引:0
|
作者
Abdi Ghaffari
Nichole Peterson
Kasra Khalaj
Natasha Vitkin
Andrew Robinson
Julie-Ann Francis
Madhuri Koti
机构
[1] Queen’s University,Department of Biomedical and Molecular Sciences
[2] Queen’s University,Department of Obstetrics and Gynecology, Kingston Health Sciences Center
[3] Queen’s University,Department of Oncology, Kingston Health Sciences Center
[4] Queen’s University,Cancer Biology and Genetics, Queen’s Cancer Research Institute
来源
British Journal of Cancer | 2018年 / 119卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:440 / 449
页数:9
相关论文
共 50 条
  • [31] Peritoneal tumor spread in high-grade serous ovarian cancer: Differences in the immune response.
    Auer, Katharina
    Bachmayr-Heyda, Anna
    Sukhbaatar, Nyamdelger
    Aust, Stefanie
    Grimm, Christoph
    Horvat, Reinhard
    Pils, Dietmar
    CLINICAL CANCER RESEARCH, 2016, 22
  • [32] PD-1 blockade enhances synergistic killing of ovarian tumour cells by combination chemotherapy and T cell immunotherapy
    Wahba, J.
    Natoli, M.
    Whilding, L.
    Parente-Pereira, A.
    Maher, J.
    Smith, R.
    Ghaem-Maghami, S.
    EUROPEAN JOURNAL OF CANCER, 2016, 61 : S218 - S218
  • [33] Molecular predictors of the outcome of paclitaxel plus carboplatin neoadjuvant therapy in high-grade serous ovarian cancer patients
    Anna P. Sokolenko
    Tatiana V. Gorodnova
    Ilya V. Bizin
    Ekaterina Sh. Kuligina
    Khristina B. Kotiv
    Alexandr A. Romanko
    Tatiana I. Ermachenkova
    Alexandr O. Ivantsov
    Elena V. Preobrazhenskaya
    Tatiana N. Sokolova
    Robert V. Broyde
    Evgeny N. Imyanitov
    Cancer Chemotherapy and Pharmacology, 2021, 88 : 439 - 450
  • [34] Molecular predictors of the outcome of paclitaxel plus carboplatin neoadjuvant therapy in high-grade serous ovarian cancer patients
    Sokolenko, Anna P.
    Gorodnova, Tatiana, V
    Bizin, Ilya, V
    Kuligina, Ekaterina Sh
    Kotiv, Khristina B.
    Romanko, Alexandr A.
    Ermachenkova, Tatiana, I
    Ivantsov, Alexandr O.
    Preobrazhenskaya, Elena, V
    Sokolova, Tatiana N.
    Broyde, Robert, V
    Imyanitov, Evgeny N.
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2021, 88 (03) : 439 - 450
  • [35] Anti-PD-1 immune checkpoint blockade-based therapy using pembrolizumab in a patient with high-grade glioblastoma
    Payandeh, Mehrdad
    Karami, Afshin
    Bavarsad, Sareh Bakhshandeh
    Asadollahi, Samira
    Jafari, Mahboobeh
    Karami, Noorodin
    BIOMEDICAL RESEARCH AND THERAPY, 2023, 10 (05): : 5680 - 5685
  • [36] PD-L1 Expression in High-Grade Serous and Clear Cell Ovarian Cancer
    Ljubiša Jovanović
    Andja Ćirković
    Milena Jović
    Radmila Janković
    Indian Journal of Gynecologic Oncology, 2022, 20
  • [37] Cancer cell genotype associated tumor immune microenvironment exhibits differential response to therapeutic STING pathway activation in high-grade serous ovarian cancer
    Shakfa, Noor
    Li, Deyang
    Conseil, Gwenaelle
    Lightbody, Elizabeth D.
    Wilson-Sanchez, Juliette
    Hamade, Ali
    Chenard, Stephen
    Jawa, Natasha A.
    Laight, Brian J.
    Afriyie-Asante, Afrakoma
    Tyryshkin, Kathrin
    Koebel, Martin
    Koti, Madhuri
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2023, 11 (04)
  • [38] PD-L1 Expression in High-Grade Serous and Clear Cell Ovarian Cancer
    Jovanovic, Ljubisa
    Cirkovic, Andja
    Jovic, Milena
    Jankovic, Radmila
    INDIAN JOURNAL OF GYNECOLOGIC ONCOLOGY, 2022, 20 (04)
  • [39] STAT1 associated immune checkpoint expression and immune cell localization represent adaptive immune resistance in high-grade serous ovarian cancer
    Li, Deyang
    Vidotto, Thiago
    Shakfa, Noor
    Afriyie-Asante, Afrakoma
    Peterson, Nichole
    de Ladurantaye, Manon
    Mes-Masson, Anne-Marie
    Francis, Julie-Ann
    Koti, Madhuri
    JOURNAL OF IMMUNOLOGY, 2021, 206
  • [40] Expression of programmed cell death ligand 1 and immune checkpoint markers in residual tumors after neoadjuvant chemotherapy for advanced high-grade serous ovarian cancer
    Kim, Hyun-Soo
    Kim, Ji-Ye
    Lee, Yong Jae
    Kim, So Hee
    Lee, Jung-Yun
    Nam, Eun Ji
    Kim, Sunghoon
    Kim, Sang Wun
    Kim, Young Tae
    GYNECOLOGIC ONCOLOGY, 2018, 151 (03) : 414 - 421