Factor Xa and thrombin induce epithelial-mesenchymal transition by retinal pigment epithelial cells via PDGF-Rβ signaling

被引：0
|
作者：
Jeroen Bastiaans
Jan C van Meurs
Conny van Holten-Neelen
Nicole MA Nagtzaam
P Martin van Hagen
Herbert Hooijkaas
Willem A Dik
机构：
[1] The Rotterdam Eye Hospital,Dept. of Immunology
[2] Erasmus MC,Dept. of Internal Medicine
[3] Erasmus MC,Dept. of Ophthalmology
[4] Erasmus MC,undefined
来源：
Journal of Translational Medicine | / 10卷 / Suppl 3期
关键词：
Thrombin; Retinal Pigment Epithelial; Retinal Detachment; Retinal Pigment Epithelial Cell; Subretinal Fluid;
D O I：
10.1186/1479-5876-10-S3-P1
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] LYTAK1 attenuates proliferation of retinal pigment epithelial cells through TGF-β-mediated epithelial-mesenchymal transition via the ERK/AKT signaling pathway
    Chen, Zhen
    Ni, Ninghua
    Mei, Yan
    Yang, Zhengrong
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2017, 14 (05) : 4951 - 4957
  • [42] Modulation of Epithelial Mesenchymal Transition (EMT) Through the Notch Signaling Pathway in Human Retinal Pigment Epithelial Cells
    Yin, Jinggang
    Yue, Junming
    Zhao, Gunnan
    Huo, Wenying
    Huo, Weihong
    Chaum, Edward
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2016, 57 (12)
  • [43] KRT8 phosphorylation regulates the epithelial-mesenchymal transition in retinal pigment epithelial cells through autophagy modulation
    Miao, Qi
    Xu, Yufeng
    Yin, Houfa
    Zhang, Huina
    Ye, Juan
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2020, 24 (05) : 3217 - 3228
  • [44] Eupatilin attenuates TGF-β2-induced proliferation and epithelial-mesenchymal transition of retinal pigment epithelial cells
    Cinar, Ayca Kupeli
    Ozal, S. Altan
    Serttas, Riza
    Erdogan, Suat
    CUTANEOUS AND OCULAR TOXICOLOGY, 2021, 40 (02) : 103 - 114
  • [45] Nintedanib inhibits normal human vitreous-induced epithelial-mesenchymal transition in human retinal pigment epithelial cells
    Yin, Yiwei
    Liu, Shikun
    Liu, Hanhan
    Wu, Wenyi
    BIOMEDICINE & PHARMACOTHERAPY, 2023, 166
  • [46] High glucose-induced epithelial-mesenchymal transition contributes to the upregulation of fibrogenic factors in retinal pigment epithelial cells
    Che, Di
    Zhou, Ti
    Lan, Yuqing
    Xie, Jinye
    Gong, Haijun
    Li, Chaoyang
    Feng, Juan
    Hong, Honghai
    Qi, Weiwei
    Ma, Caiqi
    Wu, Qiyuan
    Yang, Xia
    Gao, Guoquan
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2016, 38 (06) : 1815 - 1822
  • [47] Epithelial-Mesenchymal Transition and Proliferation of Retinal Pigment Epithelial Cells Initiated upon Loss of Cell-Cell Contact
    Tamiya, Shigeo
    Liu, LanHsin
    Kaplan, Henry J.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2010, 51 (05) : 2755 - 2763
  • [48] Mitochondrial Dysfunction During TGF-β1-Induced Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells
    Cheng, Xinyi
    Gu, Xunyi
    Wang, Fang
    CURRENT EYE RESEARCH, 2025,
  • [49] Loss of Cell-Cell Contact Initiates Epithelial-Mesenchymal Transition and Proliferation of Retinal Pigment Epithelial (RPE) Cells
    Tamiya, S.
    Liu, L.
    Dean, D. C.
    Kaplan, H. J.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2010, 51 (13)
  • [50] Loss of Prom1 impairs autophagy and promotes epithelial-mesenchymal transition in mouse retinal pigment epithelial cells
    Bhattacharya, Sujoy
    Yin, Jinggang
    Huo, Weihong
    Chaum, Edward
    JOURNAL OF CELLULAR PHYSIOLOGY, 2023, 238 (10) : 2373 - 2389
12345