Type 2 diabetes: Microbial metabolite impairs insulin signaling

被引：0
|
作者：
Crunkhorn S.
机构：
来源：
Nature Reviews Drug Discovery | 2018年 / 17卷 / 12期
关键词：
D O I：
10.1038/nrd.2018.215
中图分类号：
学科分类号：
摘要：
[No abstract available]
引用
收藏
页码：864 / 864
相关论文
共 50 条
  • [21] Cellular stress impairs insulin signaling
    Kanety, H
    Hemi, R
    Paz, K
    Karasik, A
    DIABETOLOGIA, 1998, 41 : A34 - A34
  • [22] Basal and insulin stimulated levels of insulin signaling proteins in skeletal muscle in type 2 diabetes mellitus
    Yu, YG
    Ofrecio, J
    Frias, JP
    Worrall, DS
    Kruszynska, YT
    DIABETES, 2000, 49 : A85 - A85
  • [23] Basal and insulin stimulated levels of insulin signaling proteins in skeletal muscle in Type 2 diabetes.
    Worrall, DS
    Yu, J
    Ofrecio, J
    Frias, J
    Olefsky, JM
    Kruszynska, YT
    JOURNAL OF INVESTIGATIVE MEDICINE, 2000, 48 (01) : 75A - 75A
  • [24] Imbalanced Insulin Actions in Obesity and Type 2 Diabetes: Key Mouse Models of Insulin Signaling Pathway
    Kubota, Tetsuya
    Kubota, Naoto
    Kadowaki, Takashi
    CELL METABOLISM, 2017, 25 (04) : 797 - 810
  • [25] Human Muscle Fiber Type-Specific Insulin Signaling: Impact of Obesity and Type 2 Diabetes
    Albers, Peter H.
    Pedersen, Andreas J. T.
    Birk, Jesper B.
    Kristensen, Dorte E.
    Vind, Birgitte F.
    Baba, Otto
    Nohr, Jane
    Hojlund, Kurt
    Wojtaszewski, Jorgen F. P.
    DIABETES, 2015, 64 (02) : 485 - 497
  • [26] Alterations of insulin signaling in type 2 diabetes: A review of the current evidence from humans
    Froejdoe, Sara
    Vidal, Hubert
    Pirola, Luciano
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2009, 1792 (02): : 83 - 92
  • [27] Targeting the ERK signaling pathway as a potential treatment for insulin resistance and type 2 diabetes
    Ozaki, Kei-ichi
    Awazu, Midori
    Tamiya, Mayuko
    Iwasaki, Yuka
    Harada, Aya
    Kugisaki, Satomi
    Tanimura, Susumu
    Kohno, Michiaki
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2016, 310 (08): : E643 - E651
  • [28] Functional Activity of the Insulin Signaling System of the Brain in Health and Type 2 Diabetes Mellitus
    Shpakov A.O.
    Neuroscience and Behavioral Physiology, 2017, 47 (2) : 190 - 203
  • [29] Effect of muraglitazar on insulin signaling in skeletal muscle of subjects with type 2 diabetes mellitus
    Tantiwong, Puntip
    Fernandez, Marianella
    Coletta, Dawn K.
    Sriwijitkamol, Apiradee
    Cersosimo, Eugenio
    Defronzo, Ralph A.
    Musi, Nicolas
    DIABETES, 2008, 57 : A169 - A169
  • [30] A metabolite ratio associates with measures of insulin secretion and altered risk of type 2 diabetes; a DIRECT study
    't Hart, L. M.
    Molnos, S.
    Eekhoff, E.
    Flogel, A.
    Grallert, H.
    Wahl, S.
    McCarthy, M. I.
    Gupta, R.
    Pearson, E. R.
    Much, D.
    Hummel, S.
    Beckman, M.
    Adamski, J.
    DIABETOLOGIA, 2016, 59 : S142 - S143
12345