Optical resolution of 2-(3-indolyl)propionic acid with Mucor javanicus and α-chymotrypsin

被引：0
|
作者：
Katsuya Kato
Yue-fa Gong
Satoko Tanaka
Masato Katayama
Hiroshi Kimoto
机构：
[1] National Industrial Research Institute of Nagoya,Department of Chemistry
来源：
Biotechnology Letters | 1999年 / 21卷
关键词：
α-chymotrypsin; Mucor javanicus; optical resolution; 2-(3-indolyl)propionic acid;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Resolution of 2-(3-indolyl)propionic acid was achieved via biocatalytic hydrolysis of its chloroethyl ester. Of the enzymes tested, Mucor javanicus lipase (R selectivity) and α-chymotrypsin (S selectivity) had high reactivity and enantioselectivity (E value > 50). Neither enzyme showed enantioselectivity (E value = 1) for 2-phenylpropionic acid.
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页码：457 / 461
页数：4
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