Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal

被引：0

作者：

J. Michael Krill-Burger

Joshua M. Dempster

Ashir A. Borah

Brenton R. Paolella

David E. Root

Todd R. Golub

Jesse S. Boehm

William C. Hahn

James M. McFarland

Francisca Vazquez

Aviad Tsherniak

机构：

[1] Broad Institute of Harvard and MIT,

[2] Dana-Farber Cancer Institute,undefined

[3] Harvard Medical School,undefined

来源：

Genome Biology | / 24卷

关键词：

Functional genomics; Cancer genomics; Target identification; RNAi; CRISPR-Cas systems; CRISPR-Cas9 genome editing; Drug discovery;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

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