Unravelling leptin variants: advancing precision medicine in obesity

被引：0
|
作者：
Béatrice Dubern
Karine Clément
机构：
[1] Assistance Publique-Hôpitaux de Paris,Nutrition and Obesities: Systemic Approaches Research Unit (Nutriomics)
[2] French Reference Center for Prader-Willi Syndrome and other rare obesities (PRADORT),undefined
[3] Sorbonne Université,undefined
[4] INSERM,undefined
来源：
Nature Reviews Endocrinology | 2023年 / 19卷
关键词：
D O I：
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中图分类号：
学科分类号：
摘要：
Funcke et al. shed light on the management of leptin replacement therapy in monogenic obesity by identifying two LEP variants with antagonistic functional effects. Their groundbreaking study emphasizes the urgent need for in-depth understanding of the genetic factors involved in obesity to pave the way for tailored interventions.
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页码：562 / 563
页数：1
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