Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells

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作者
Helena Gbelcová
Silvie Rimpelová
Zdeněk Knejzlík
Jana Šáchová
Michal Kolář
Hynek Strnad
Vanda Repiská
Walter Cosimo D’Acunto
Tomáš Ruml
Libor Vítek
机构
[1] Comenius University,Institute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine
[2] University of Chemistry and Technology,Department of Biochemistry and Microbiology
[3] Laboratory of Genomics and Bioinformatics,Institute of Medical Biochemistry and Laboratory Diagnostics, and 4th Department of Internal Medicine, 1st Faculty of Medicine
[4] Institute of Molecular Genetics of the Academy of Sciences of the Czech Republic,undefined
[5] Charles University,undefined
关键词
Farnesyl pyrophosphate; Gene expression; Geranylgeranyl pyrophosphate; HMG-CoA reductase inhibitors; Isoprenoids; oncogene; Mevalonate; Pancreatic cancer; Prenylation; Statins;
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