Locus-specific chromatin isolation

被引：0
|
作者：
Michiel Vermeulen
Jérôme Déjardin
机构：
[1] Radboud University,Department of Molecular Biology, Radboud Institute for Molecular Life Sciences, Oncode Institute
[2] CNRS-Université de Montpellier,Institute of Human Genetics
来源：
Nature Reviews Molecular Cell Biology | 2020年 / 21卷
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学科分类号：
摘要：
Identifying factors bound to specific genomic loci in an unbiased manner is the holy grail of chromatin research, because it would provide an ultimate description of locus function. In this Comment, we explain why purifying a single locus represents a major technical challenge and provide recommendations for achieving this goal.
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页码：249 / 250
页数：1
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