BAP1 and PBRM1 in metastatic clear cell renal cell carcinoma: tumor heterogeneity and concordance with paired primary tumor

被引：0
|
作者：
Jeanette E. Eckel-Passow
Daniel J. Serie
John C. Cheville
Thai H. Ho
Payal Kapur
James Brugarolas
R. Houston Thompson
Bradley C. Leibovich
Eugene D. Kwon
Richard W. Joseph
Alexander S. Parker
机构：
[1] Mayo Clinic,Division of Biomedical Statistics and Informatics
[2] Mayo Clinic,Department of Health Sciences Research
[3] Mayo Clinic,Laboratory Medicine and Pathology
[4] Mayo Clinic,Division of Hematology and Medical Oncology
[5] University of Texas Southwestern Medical Center,Department of Pathology
[6] University of Texas Southwestern Medical Center,Kidney Cancer Program, Simmons Comprehensive Cancer Center
[7] University of Texas Southwestern Medical Center,Division of Hematology
[8] Mayo Clinic,Oncology
[9] Mayo Clinic,Department of Urology
来源：
BMC Urology | / 17卷
关键词：
Clonal; Prognostic; Immunohistochemistry;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Differential overall survival results in RECORD-3 study based on three distinct clear cell metastatic renal cell carcinoma molecular subgroups classified by BAP1 and/or PBRM1 mutations
    Hsieh, James
    Chen, David
    Wang, Patricia
    Chen, Ying-Bei
    Mahtab, Marker
    Pate, Parul
    Bhanot, Umesh
    Berger, Michael
    Cheng, Emily
    Knox, Jennifer
    Voss, Martin
    Voi, Maurizio
    Motzer, Robert
    [J]. BJU INTERNATIONAL, 2016, 118 : 10 - 10
  • [32] Clinical and pathological impact of VHL, PBRM1, BAP1, SETD2, KDM6A, and JARID1c in clear cell renal cell carcinoma
    Gossage, Lucy
    Murtaza, Muhammed
    Slatter, Andrew F.
    Lichtenstein, Conrad P.
    Warren, Anne
    Haynes, Beverley
    Marass, Francesco
    Roberts, Ian
    Shanahan, Susan J.
    Claas, Andreas
    Dunham, Andrew
    May, Andrew P.
    Rosenfeld, Nitzan
    Forshew, Tim
    Eisen, Tim
    [J]. GENES CHROMOSOMES & CANCER, 2014, 53 (01): : 38 - 51
  • [33] Angiogenic and T-effector subgroups identified by gene expression profiling (GEP) and propensity for PBRM1 and BAP1 alterations in clear cell renal cell carcinoma (ccRCC).
    Barata, Pedro C.
    Gulati, Shuchi
    Elliott, Andrew
    Rao, Arpit
    Hammers, Hans J.
    Quinn, David I.
    Gartrell, Benjamin Adam
    Zibelman, Matthew R.
    Wei Shuanzeng
    Geynisman, Daniel M.
    Zhang Tian
    Darabi, Sourat
    Dawson, Nancy Ann
    Hauke, Ralph J.
    Poorman, Kelsey Anne
    Nabhan, Chadi
    Ryan, Charles J.
    Heath, Elisabeth I.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (06)
  • [34] The role of PBRM1 as tumor suppressor gene in renal cell carcinomas
    Jandrig, Burkhard
    Ikromov, Odiljon
    Hoegner, Anica
    Wendler, Johann J.
    Schostak, Martin
    Krause, Hans
    [J]. CANCER RESEARCH, 2014, 74 (19)
  • [35] PBRM1 and KDM5C loss modulate the tumor immune microenvironment of clear cell renal carcinoma
    Valdivia, Carlos
    de Nicolas-Hernandez, Javier
    Lanillos, Javier
    Martinez-Montes, Angel M.
    Arenas, Alicia
    Mellid, Sara
    Monteagudo, Maria
    Torres, Raul
    Jose Caleiras-Pires, Eduardo
    Leandro, Javier
    Robledo, Mercedes
    Rodriguez-Antona, Cristina
    [J]. EUROPEAN JOURNAL OF HUMAN GENETICS, 2024, 32 : 68 - 69
  • [36] PBRM1 Immunohistochemical Expression Profile Correlates with Histomorphological Features and Endothelial Expression of Tumor Vasculature for Clear Cell Renal Cell Carcinoma
    Saiga, Kazuho
    Ohe, Chisato
    Yoshida, Takashi
    Ohsugi, Haruyuki
    Ikeda, Junichi
    Atsumi, Naho
    Noda, Yuri
    Yasukochi, Yoshiki
    Higasa, Koichiro
    Taniguchi, Hisanori
    Kinoshita, Hidefumi
    Tsuta, Koji
    [J]. CANCERS, 2022, 14 (04)
  • [37] Prognostic value of BAP1 expression in clear cell renal cell carcinoma with inferior vena cava tumor thrombosis.
    Oka, Suguru
    Inoshita, Naoko
    Miura, Yuji
    Oki, Ryosuke
    Miyama, Yu
    Nagamoto, Shoichi
    Ogawa, Kohei
    Sakaguchi, Kazushige
    Kondoh, Chihiro
    Kurosawa, Kazuhiro
    Urakami, Shinji
    Takano, Toshimi
    Okaneya, Toshikazu
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
  • [38] Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL-/- clear cell renal carcinoma
    Gao, Wenhua
    Li, Wei
    Xiao, Tengfei
    Liu, Xiaole Shirley
    Kaelin, William G., Jr.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (05) : 1027 - 1032
  • [39] PBRM1 Regulates the Expression of Genes Involved in Metabolism and Cell Adhesion in Renal Clear Cell Carcinoma
    Chowdhury, Basudev
    Porter, Elizabeth G.
    Stewart, Jane C.
    Ferreira, Christina R.
    Schipma, Matthew J.
    Dykhuizen, Emily C.
    [J]. PLOS ONE, 2016, 11 (04):
  • [40] BAP1 LOSS IS ASSOCIATED WITH METASTASIS IN ADVANCED CLEAR CELL RENAL CELL CARCINOMA
    Khaleel, Sari
    Reiner, Anne
    Brennan, Cameron
    Hussain, Ibrahim
    Berman, Samuel
    Hakimi, Ari
    Moss, Nelson
    [J]. JOURNAL OF UROLOGY, 2022, 207 (05): : E1018 - E1018
12345