Molecular Markers of Tumors

被引：0
|
作者：
N. E. Kushlinsky
E. S. Gershtein
L. K. Ovchinnikova
M. A. Digaeva
机构：
[1] Russian Academy of Medical Sciences,N. N. Blokhin Russian Cancer Research Center
来源：
Bulletin of Experimental Biology and Medicine | 2009年 / 148卷
关键词：
molecular markers of tumors; steroid hormone receptors; growth factors; growth factor receptors; proteinkinases; tumor-associated proteases; angiogenesis markers; microchips;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The main biologically significant molecular markers of human tumors are discussed on the basis of modern published data and author’s findings of many-year studies: steroid hormone receptors, growth factors and underlying signal proteins, tumor-associated proteases, and angiogenesis markers. Methodological aspects, progress in preclinical studies, international recommendations on the use of these parameters for prediction of the disease course and prescription of effective therapy are analyzed. Latest data on the potentialities and limitations of modern highly productive technologies (microchips) as an alternative to studies of individual molecular markers are presented.
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