Expression of Immunomodulator Gene mRNA in Co-Culture of Mesenchymal Stromal Cells from the Placenta and Human Mononuclear Blood Cells

被引：0
|
作者：
A. M. Savilova
M. M. Chulkina
V. N. Veryasov
M. N. Gordeeva
D. Yu. Trofimov
G. T. Sukhikh
机构：
[1] Ministry of Health of the Russian Federation,V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology
来源：
Bulletin of Experimental Biology and Medicine | 2015年 / 158卷
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摘要：
The expression of mRNA of cytokines and immunoregulatory molecules characterizing the interaction of mesenchymal stromal cells from chorionic villi of postpartum placenta and allogenic mononuclear blood cells was studied during 3-day co-culturing of these cells. The expression of foxp3, il2ra, and il10 mRNA in floating mononuclear cells increased from day 1 to 3 in co-culture, which can refl ect the process of induction of regulatory T cells in the lymphocyte population under the action of mesenchymal stromal cells.
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页码：561 / 565
页数：4
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