Muscle development during vertebrate limb outgrowth

被引:0
|
作者
D. Büscher
Juan Carlos Izpisúa Belmonte
机构
[1] The Salk Institute for Biological Studies,
[2] Gene Expression Laboratory,undefined
[3] 10010 N. Torrey Pines Road,undefined
[4] La Jolla,undefined
[5] CA 92037-1099,undefined
[6] USA e-mail: dbuscher@aim.salk.edu; Tel.: +1 619 453 4100,undefined
[7] ext. 1324; Fax: +1 619 455 1349,undefined
来源
Cell and Tissue Research | 1999年 / 296卷
关键词
Key words Limb; Development; Myogenesis; Vertebrate; Transcription factors; Somites;
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学科分类号
摘要
Limb development has become one of the model systems for studying vertebrate development. One crucial aspect in limb development is the origin, differentiation and patterning of muscle. Much progress has been made in recent years towards understanding this process. One of the general observations is that the genes involved in limb muscle development appear to be very similar to those involved in muscle development in other regions of the embryo. In this review, we summarize some of the genes and mechanisms that regulate limb muscle development and discuss various avenues along which a deeper understanding can be gained of how muscle cells originate and differentiate in different tissues during vertebrate development.
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页码:131 / 139
页数:8
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