Glucose Metabolism in Healthy Subjects and in Patients with Carbohydrate and Lipid Metabolic Disorders

被引：0
|
作者：
E. I. Sokolov
A. L. Davydov
N. T. Starkova
A. M. Zyakun
E. I. Maevskii
E. V. Grishina
机构：
[1] Moscow State Medical and Stomatological University,Institute of Biochemistry and Physiology of Microorganisms
[2] Russian Academy of Sciences,Institute of Theoretical and Experimental Biophysics
[3] Russian Academy of Sciences,undefined
来源：
Human Physiology | 2002年 / 28卷 / 6期
关键词：
Glucose; Lipid; Obesity; Diabetes Mellitus; Carbohydrate;
D O I：
10.1023/A:1021120910665
中图分类号：
学科分类号：
摘要：
The rate of glucose oxidation was studied by measurement of the 13C concentration in expired air with simultaneous detection of the activity of the pyruvate dehydrogenase complex in subjects with obesity and patients with type II diabetes. Intake of small amounts of glucose did not change the rate of glucose oxidation in subjects with obesity as compared to healthy controls. However, intake of large amounts of glucose resulted in a considerable increase in the rate of glucose oxidation without a hypoxic shift. In patients with diabetes mellitus, the rate of glucose oxidation decreased with increasing tissue hypoxia.
引用
收藏
页码：743 / 746
页数：3
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