Activating the Hippo pathway by nevadensin overcomes Yap-drived resistance to sorafenib in hepatocellular carcinoma

被引：0
|
作者：
Hewen Shi
Ying Zou
Xiaoxue Wang
Guoli Wang
Yijia Gao
Fan Yi
junqing Xu
Yancun Yin
Defang Li
Minjing Li
机构：
[1] Binzhou Medical University,Featured Laboratory for Biosynthesis and Target Discovery of Active Components of Traditional Chinese Medicine, School of Integrated Traditional Chinese and Western Medicine
[2] Binzhou Medical University,School of Basic Medical Sciences
[3] Qingdao University Medical College,Department of Hematology
[4] Affiliated Yantai Yuhuangding Hoepital,undefined
来源：
Discover Oncology | / 14卷
关键词：
Hippo pathway; Nevadensin; YAP; Sensitization;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Mechanisms of sorafenib resistance in hepatocellular carcinoma
    Liang, Yuanjing
    CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY, 2024, 48 (08)
  • [32] CD24 regulates sorafenib resistance via activating autophagy in hepatocellular carcinoma
    Shuai Lu
    Yao Yao
    Guolong Xu
    Chao Zhou
    Yuan Zhang
    Jie Sun
    Runqiu Jiang
    Qing Shao
    Yun Chen
    Cell Death & Disease, 9
  • [33] CD24 regulates sorafenib resistance via activating autophagy in hepatocellular carcinoma
    Lu, Shuai
    Yao, Yao
    Xu, Guolong
    Zhou, Chao
    Zhang, Yuan
    Sun, Jie
    Jiang, Runqiu
    Shao, Qing
    Chen, Yun
    CELL DEATH & DISEASE, 2018, 9
  • [34] Tadalafil enhances the therapeutic efficacy of BET inhibitors in hepatocellular carcinoma through activating Hippo pathway
    Kong, Deqiang
    Jiang, Yuancong
    Miao, Xiaolong
    Wu, Zelai
    Liu, Han
    Gong, Weihua
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2021, 1867 (12):
  • [35] The role of the Hippo/YAP pathway in cancer drug resistance.
    Bivona, Trever
    MOLECULAR CANCER RESEARCH, 2020, 18 (08) : 17 - 17
  • [36] Inactivation of hypoxia-induced YAP by statins overcomes hypoxic resistance tosorafenib in hepatocellular carcinoma cells
    Tian-yi Zhou
    Lin-han Zhuang
    Yan Hu
    Yu-lu Zhou
    Wen-kai Lin
    Dan-dan Wang
    Zi-qian Wan
    Lin-lin Chang
    Ying Chen
    Mei-dan Ying
    Zi-bo Chen
    Song Ye
    Jian-shu Lou
    Qiao-jun He
    Hong Zhu
    Bo Yang
    Scientific Reports, 6
  • [37] Inactivation of hypoxia-induced YAP by statins overcomes hypoxic resistance tosorafenib in hepatocellular carcinoma cells
    Zhou, Tian-yi
    Zhuang, Lin-han
    Hu, Yan
    Zhou, Yu-lu
    Lin, Wen-kai
    Wang, Dan-dan
    Wan, Zi-qian
    Chang, Lin-lin
    Chen, Ying
    Ying, Mei-dan
    Chen, Zi-bo
    Ye, Song
    Lou, Jian-shu
    He, Qiao-jun
    Zhu, Hong
    Yang, Bo
    SCIENTIFIC REPORTS, 2016, 6
  • [38] MCM2 promotes the stemness and sorafenib resistance of hepatocellular carcinoma cells via hippo signaling
    Zhou, Xin
    Luo, Jianzhu
    Xie, Haixiang
    Wei, Zhongliu
    Li, Tianman
    Liu, Junqi
    Liao, Xiwen
    Zhu, Guangzhi
    Peng, Tao
    CELL DEATH DISCOVERY, 2022, 8 (01)
  • [39] Inhibition of LPAR6 overcomes sorafenib resistance by switching glycolysis into oxidative phosphorylation in hepatocellular carcinoma
    Gnocchi, Davide
    Kurzyk, Agata
    Mintrone, Antonella
    Lentini, Giovanni
    Sabba, Carlo
    Mazzocca, Antonio
    BIOCHIMIE, 2022, 202 : 180 - 189
  • [40] TFAM depletion overcomes hepatocellular carcinoma resistance to doxorubicin and sorafenib through AMPK activation and mitochondrial dysfunction
    Zhu, Ying
    Xu, Jianguo
    Hu, Wei
    Wang, Fang
    Zhou, Yan
    Xu, Wen
    Gong, Wei
    Shao, Lichun
    GENE, 2020, 753
12345