Design and Simulation of a High Sensitive Surface Plasmon Resonance Biosensor for Detection of Biomolecules

In this paper, a surface plasmon resonance (SPR) biosensor based on black phosphorus (BP)–WSe2 coated metal surface for the detection of biomolecules is designed and simulated. The reported sensor configuration consists of a prism (SF10 glass), ZnO (zinc oxide), gold (Au), WSe2–BP, and sensing medium. The execution parameters including sensitivity, detection accuracy, and quality factor of the proposed sensor are explored at an operating wavelength of 633 nm. The angular interrogation method is used for the reflectance spectra analysis. The overall simulation is performed by COMSOL multiphysics (5.3a). Numerical outcomes demonstrate that the base ZnO layers which have an expansive genuine value of the dielectric constant in a mix with gold, WSe2, and BP are in charge of upgrading the detecting execution of the proposed SPR based biosensor. The reported biosensor achieves maximum sensitivity of 101.5 deg/RIU, the detection accuracy of 1.57 and a quality parameter of 15.62 RIU−1 for a large dynamic range of refractive index differing from 1.33 to 1.43.