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Natl Inst Canc, Unit Biomed Res Canc, Translat & Canc Lab, Inst Nacl Cancerol, 22 San Fernando Ave, Mexico City 14080, Mexico Natl Inst Canc, Unit Biomed Res Canc, Translat & Canc Lab, Inst Nacl Cancerol, 22 San Fernando Ave, Mexico City 14080, Mexico