Simvastatin suppresses vascular inflammation and atherosclerosis in ApoE−/− mice by downregulating the HMGB1-RAGE axis

被引:0
|
作者
Ming Liu
Ying Yu
Hong Jiang
Lei Zhang
Pei-pei Zhang
Peng Yu
Jian-guo Jia
Rui-zhen Chen
Yun-zeng Zou
Jun-bo Ge
机构
[1] Shanghai Institute of Cardiovascular Diseases,
[2] Zhongshan Hospital,undefined
[3] Shanghai Medical College,undefined
[4] Fudan University,undefined
[5] Ministry of Public Health Key Laboratory of Heart Diseases,undefined
[6] Zhongshan Hospital,undefined
[7] Shanghai Medical College,undefined
[8] Fudan University,undefined
来源
Acta Pharmacologica Sinica | 2013年 / 34卷
关键词
atherosclerosis; inflammation; simvastatin; ApoE; mice; human umbilical vein endothelial cells (HUVECs); aortic sinus; HMGB1; RAGE; VCAM-1; MCP-1; macrophages;
D O I
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中图分类号
学科分类号
摘要
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页码:830 / 836
页数:6
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